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    Experimental candidiasis in mice: evaluation of the histopathology and the effect of cysteine on the virulence of candida albicans

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    Date Issued
    1962
    Author(s)
    De Palma, Philip A
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    Permanent Link
    https://hdl.handle.net/2144/28116
    Abstract
    Normal strains of Candida albicans reproduce by budding when conditions are favorable for growth. In animal tissues a rapid morphological chance takes place budding cells fail to detach and pseudouyphae develop. The addition of cysteine to the normal growth medium of a genetically blocked, filamentous strain of Candida albicans results in a suppresion of the filamentous phase and an increased number of budding yeast forms. Filamentous variants of Candida albicans have not demonstrated appreciable virulence in experimental infections, but tLere is evidence that induced yeast growth under the influence of cysteine accompanies an increase in virulence.
    Description
    Thesis (M.A.)--Boston University.
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    Based on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.
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    • Dissertations and Theses (pre-1964) [13090]


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