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    Silicon-based nanochannel glucose sensor

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    Date Issued
    2008-01-07
    Publisher Version
    10.1063/1.2832648
    Author(s)
    Wang, Xihua
    Chen, Yu
    Gibney, Katherine A.
    Erramilli, Shyamsunder
    Mohanty, Pritiraj
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    Permanent Link
    https://hdl.handle.net/2144/28280
    Citation (published version)
    Xihua Wang, Yu Chen, Katherine A Gibney, Shyamsunder Erramilli, Pritiraj Mohanty. 2008. "Silicon-based nanochannel glucose sensor." Appl. Phys. Lett. 92, 013903 (2008); https://doi.org/10.1063/1.2832648
    Abstract
    Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The differential conductance of silicon nanowires, tuned with source-drain bias voltage, is demonstrated to be sensitive to the biocatalyzed oxidation of glucose. The glucose biosensor response is linear in the 0.5–8mM concentration range with 3–5min response time. This silicon nanochannel-based glucose biosensor technology offers the possibility of high density, high quality glucose biosensor integration with silicon-based circuitry.
    Rights
    © 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing.
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    • BU Open Access Articles [3866]
    • CAS: Physics: Scholarly Papers [356]


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