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dc.contributor.authorChen, Yuen_US
dc.contributor.authorWang, Xihuaen_US
dc.contributor.authorHong, Mi K.en_US
dc.contributor.authorErramilli, Shyamsunderen_US
dc.contributor.authorMohanty, Pritirajen_US
dc.contributor.authorRosenberg, Carolen_US
dc.date.accessioned2018-04-12T19:34:27Z
dc.date.available2018-04-12T19:34:27Z
dc.date.issued2007-12-10
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000251678700083&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=6e74115fe3da270499c3d65c9b17d654
dc.identifier.citationYu Chen, Xihua Wang, Mi K Hong, Shyamsunder Erramilli, Pritiraj Mohanty, Carol Rosenberg. 2007. "Nanoscale field effect transistor for biomolecular signal amplification." Appl. Phys. Lett. 91, 243511; https://doi.org/10.1063/1.2822445
dc.identifier.issn0003-6951
dc.identifier.issn1077-3118
dc.identifier.urihttps://hdl.handle.net/2144/28282
dc.description.abstractWe report amplification of biomolecular recognition signal in lithographically defined silicon nanochannel devices. The devices are configured as field effect transistors (FET) in the reversed source-drain bias region. The measurement of the differential conductance of the nanowire channels in the FET allows sensitive detection of changes in the surface potential due to biomolecular binding. Narrower silicon channels demonstrate higher sensitivity to binding due to increased surface-to-volume ratio. The operation of the device in the negative source-drain region demonstrates signal amplification. The equivalence between protein binding and change in the surface potential is described.en_US
dc.format.extentp. 243511en_US
dc.languageEnglish
dc.publisherAMER INST PHYSICSen_US
dc.relation.ispartofAPPLIED PHYSICS LETTERS
dc.rights© 2007 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing.en_US
dc.subjectScience & technologyen_US
dc.subjectPhysical sciencesen_US
dc.subjectPhysics, applieden_US
dc.subjectPhysicsen_US
dc.titleNanoscale field effect transistor for biomolecular signal amplificationen_US
dc.typeArticleen_US
dc.identifier.doi10.1063/1.2822445
pubs.elements-sourceweb-of-scienceen_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Arts & Sciencesen_US
pubs.organisational-groupBoston University, College of Arts & Sciences, Department of Physicsen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0003-3950-9122 (Erramilli, Shyamsunder)


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