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dc.contributor.authorWang, X.en_US
dc.contributor.authorDing, H.en_US
dc.contributor.authorRyan, L.en_US
dc.contributor.authorXu, X.en_US
dc.date.accessioned2012-01-09T15:41:04Z
dc.date.available2012-01-09T15:41:04Z
dc.date.issued1997-05
dc.identifier.citationWang, X, H Ding, L Ryan, X Xu. "Association Between Air Pollution and Low Birth Weight: A Community-based Study." Environmental Health Perspectives 105(5): 514-520. (1997)
dc.identifier.urihttps://hdl.handle.net/2144/2833
dc.description.abstractThe relationship between maternal exposure to air pollution during periods of pregnancy (entire and specific periods) and birth weight was investigated in a well-defined cohort. Between 1988 and 1991, all pregnant women living in four residential areas of Beijing were registered and followed from early pregnancy until delivery. Information on individual mothers and infants was collected. Daily air pollution data were obtained independently. The sample for analysis included 74,671 first-parity live births were gestational age 37-44 weeks. Multiple linear regression and logistic regression were used to estimate the effects of air pollution on birth weight and low birth weight (< 2,500 g), adjusting for gestational age, residence, year of birth, maternal age, and infant gender. There was a significant exposure-response relationship between maternal exposures to sulfur dioxide (SO2) and total suspended particles (TSP) during the third trimester of pregnancy and infant birth weight. The adjusted odds ratio for low birth weight was 1.11 (95% CI, 1.06-1.16) for each 100 micrograms/m3 increase in SO2 and 1.10 (95% CI, 1.05-1.14) for each 100 micrograms/m3 increase in TSP. The estimated reduction in birth weight was 7.3 g and 6.9 g for each 100 micrograms/m3 increase in SO2 and in TSP, respectively. The birth weight distribution of the high-exposure group was more skewed toward the left tail (i.e., with higher proportion of births < 2,500 g) than that of the low-exposure group. Although the effects of other unmeasured risk factors cannot be excluded with certainty, our data suggests that TSP and SO2, or a more complex pollution mixture associated with these pollutants, contribute to an excess risk of low birth weight in the Beijing population.en_US
dc.description.sponsorshipNational Institute of Environmental Health Sciences (ES05947, ES08337); National Institute of Child Health & Human Development (R01 HD32505); Department of Health and Human Services (MCJ-259501, HRSA 5 T32 PE10014)en_US
dc.language.isoenen_US
dc.publisherNational Institute of Environmental Health Sciencesen_US
dc.subjectAir pollutionen_US
dc.subjectBirth weighten_US
dc.subjectLow birth weighten_US
dc.subjectProspective studiesen_US
dc.subjectSulphur dioxidesen_US
dc.subjectSO2en_US
dc.subjectTotal suspended particulatesen_US
dc.subjectTSPen_US
dc.titleAssociation Between Air Pollution and Low Birth Weight: A Community-Based Studyen_US
dc.typeArticleen_US
dc.identifier.pmid9222137
dc.identifier.pmcid1469882


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