URI: http://hdl.handle.net/2144/2860

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  • The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide 

    Soscia, Stephanie J.; Kirby, James E.; Washicosky, Kevin J.; Tucker, Stephanie M.; Ingelsson, Martin; Hyman, Bradley; Burton, Mark A.; Goldstein, Lee E.; Duong, Scott; Tanzi, Rudolph E.; Moir, Robert D. (Public Library of Science, 2010-3-3)
    BACKGROUND. The amyloid β-protein (Aβ) is believed to be the key mediator of Alzheimer's disease (AD) pathology. Aβ is most often characterized as an incidental catabolic byproduct that lacks a normal physiological role. ...