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dc.contributor.authorRydingsward, Jessica E.en_US
dc.contributor.authorHorkan, Clare M.en_US
dc.contributor.authorMogensen, Kris M.en_US
dc.contributor.authorQuraishi, Sadeq A.en_US
dc.contributor.authorAmrein, Karinen_US
dc.contributor.authorChristopher, Kenneth B.en_US
dc.coverage.spatialUnited Statesen_US
dc.date.accessioned2018-07-27T12:57:58Z
dc.date.available2018-07-27T12:57:58Z
dc.date.issued2016-05
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/26929191
dc.identifier.citationJessica E Rydingsward, Clare M Horkan, Kris M Mogensen, Sadeq A Quraishi, Karin Amrein, Kenneth B Christopher. 2016. "Functional Status in ICU Survivors and Out of Hospital Outcomes: A Cohort Study.." Crit Care Med, Volume 44, Issue 5, pp. 869 - 879. http://dx.doi.org/10.1097/CCM.0000000000001627
dc.identifier.issn1530-0293
dc.identifier.urihttps://hdl.handle.net/2144/30064
dc.description.abstractOBJECTIVES: Functional status at hospital discharge may be a risk factor for adverse events among survivors of critical illness. We sought to examine the association between functional status at hospital discharge in survivors of critical care and risk of 90-day all-cause mortality after hospital discharge. DESIGN: Single-center retrospective cohort study. SETTING: Academic Medical Center. PATIENTS: Ten thousand three hundred forty-three adults who received critical care from 1997 to 2011 and survived hospitalization. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The exposure of interest was functional status determined at hospital discharge by a licensed physical therapist and rated based on qualitative categories adapted from the Functional Independence Measure. The main outcome was 90-day post hospital discharge all-cause mortality. A categorical risk-prediction score was derived and validated based on a logistic regression model of the function grades for each assessment. In an adjusted logistic regression model, the lowest quartile of functional status at hospital discharge was associated with an increased odds of 90-day postdischarge mortality compared with patients with independent functional status (odds ratio, 7.63 [95% CI, 3.83-15.22; p < 0.001]). In patients who had at least 7 days of physical therapy treatment prior to hospital discharge (n = 2,293), the adjusted odds of 90-day postdischarge mortality in patients with marked improvement in functional status at discharge was 64% less than patients with no change in functional status (odds ratio, 0.36 [95% CI, 0.24-0.53]; p < 0.001). CONCLUSIONS: Lower functional status at hospital discharge in survivors of critical illness is associated with increased postdischarge mortality. Furthermore, patients whose functional status improves before discharge have decreased odds of postdischarge mortality.en_US
dc.description.sponsorshipL30 TR001257 - NCATS NIH HHSen_US
dc.format.extentp. 869 - 879en_US
dc.languageeng
dc.relation.ispartofCrit Care Med
dc.subjectScience & technologyen_US
dc.subjectLife sciences & biomedicineen_US
dc.subjectCritical care medicineen_US
dc.subjectGeneral & internal medicineen_US
dc.subjectFunctional Independence Measureen_US
dc.subjectFunctional statusen_US
dc.subjectIntensive care unit survivoren_US
dc.subjectMortalityen_US
dc.subjectIntensive care uniten_US
dc.subjectCritically ill patientsen_US
dc.subjectAcute respiratory failureen_US
dc.subjectOlder adultsen_US
dc.subjectSevere sepsisen_US
dc.subjectEmergency departmentsen_US
dc.subjectAdulten_US
dc.subjectAge factorsen_US
dc.subjectAgeden_US
dc.subjectCritical illnessen_US
dc.subjectFemaleen_US
dc.subjectHealth statusen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectMiddle ageden_US
dc.subjectOdds ratioen_US
dc.subjectPatient dischargeen_US
dc.subjectPhysical therapy modalitiesen_US
dc.subjectRetrospective studiesen_US
dc.subjectRisk factorsen_US
dc.subjectSeverity of illness indexen_US
dc.subjectSex factorsen_US
dc.subjectSurvivorsen_US
dc.subjectTime factorsen_US
dc.subjectClinical sciencesen_US
dc.subjectNursingen_US
dc.subjectPublic health and health servicesen_US
dc.subjectEmergency & critical care medicineen_US
dc.titleFunctional status in ICU survivors and out of hospital outcomes: a cohort studyen_US
dc.typeArticleen_US
dc.identifier.doi10.1097/CCM.0000000000001627
pubs.elements-sourcepubmeden_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Health & Rehabilitation Sciences: Sargent Collegeen_US
pubs.organisational-groupBoston University, College of Health & Rehabilitation Sciences: Sargent College, Health Sciencesen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0001-9510-3018 (Mogensen, Kris M)


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