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dc.contributor.authorJalisi, Scharukhen_US
dc.contributor.authorAinsworth, Tiffinyen_US
dc.contributor.authorLaValley, Michaelen_US
dc.date.accessioned2012-01-11T16:08:09Z
dc.date.available2012-01-11T16:08:09Z
dc.date.copyright2010en_US
dc.date.issued2010-7-26en_US
dc.identifier.citationJalisi, Scharukh, Tiffiny Ainsworth, Michael LaValley. "Prognostic Outcomes of Tall Cell Variant Papillary Thyroid Cancer: A Meta-Analysis" Journal of Thyroid Research 2010:325602.en_US
dc.identifier.issn2042-0072en_US
dc.identifier.urihttps://hdl.handle.net/2144/3095
dc.description.abstractObjective. To evaluate the prognosis of tall cell variant (TCV) compared to usual variant (UV) papillary thyroid cancer by comparing disease-related mortality and recurrence data from published studies. Methods. Ovid MEDLINE keyword search using "tall cell variant papillary thyroid cancer" was used to identify studies published in English that calculated disease-related mortality and recurrence rates for both TCV and UV. Results. A total of 131 cases of tall cell variant papillary thyroid cancer were reviewed. The combined odds ratio of recurrence for TCV compared to UV is 4.50 with a 95% confidence interval from 2.90 to 6.99. For disease-related mortality, the combined odds ratio for TCV was compared to UV of 14.28 with a 95% confidence interval from 8.01 to 25.46. Conclusion. Currently published data suggests that TCV is a negative prognostic indicator in papillary thyroid cancer and requires aggressive therapy. This meta-analysis provides the largest prognostic data series on TCV in the literature and clearly identifies the need for accurate pathological identification of TCV and its further study as an independent prognostic factor.en_US
dc.language.isoenen_US
dc.publisherSAGE-Hindawi Access to Researchen_US
dc.rightsCopyright 2010 Scharukh Jalisi et al.en_US
dc.titlePrognostic Outcomes of Tall Cell Variant Papillary Thyroid Cancer: A Meta-Analysisen_US
dc.typeArticleen_US
dc.identifier.doi10.4061/2010/325602en_US
dc.identifier.pmid21048837en_US
dc.identifier.pmcid2957694en_US


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