Seroprevalence of Hepatitis E among Boston Area Travelers, 2009-2010
Barbre, Kira A.
Jentes, Emily S.
Hamer, Davidson H.
Barnett, Elizabeth D.
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Citation (published version)Kira A. Barbre, Emily S. Jentes, Jan Drobeniuc, Saleem Kamili, Davidson H. Hamer, Elizabeth D. Barnett. American Journal of Tropical Medicine and Hygience. 2017 Jan; 96(4):929-934. 10.4269/ajtmh.16-0727
We determined the prevalence of IgG antibodies to hepatitis E virus (anti-HEV IgG) among travelers attending Boston-area travel health clinics from 2009 to 2010. Pre-travel samples were available for 1,356 travelers, with paired pre- and post-travel samples for 450 (33%). Eighty of 1,356 (6%) pre-travel samples were positive for anti-HEV IgG. Compared with participants who had never lived in nor traveled to a highly endemic country, the pre-travel prevalence odds ratio (POR) of anti-HEV IgG among participants born in or with a history of previous travel to a highly endemic country was increased (POR = 4.8, 95% CI = 2.3–10.3 and POR = 2.6, 95% CI = 1.4–5.0, respectively). Among participants with previous travel to a highly endemic country, anti-HEV IgG was associated with age > 40 years (POR = 3.7, 95% CI = 1.3–10.2) and travel history to ≥ 3 highly endemic countries (POR = 2.7, 95% CI = 1.2–5.9). Two participants may have contracted HEV infection during their 2009–2010 trip.
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