Show simple item record

dc.contributor.authorAlmohaisen, Ahmeden_US
dc.date.accessioned2018-10-31T15:40:44Z
dc.date.available2018-10-31T15:40:44Z
dc.date.issued2006
dc.date.submitted2006
dc.identifier.other(OCoLC)77712374
dc.identifier.otherb27070694
dc.identifier.urihttps://hdl.handle.net/2144/31720
dc.descriptionPLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please click Download and log in with a valid BU account to access. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.en_US
dc.descriptionThesis (MSD)--Boston University, Henry M. Goldman School of Dental Medicine (Prosthodontics).en_US
dc.descriptionIncludes bibliographical references: leaves 30-40.en_US
dc.description.abstractMucus serves several protective functions within the human body , such as hydrating the epithelium and trapping foreign substances for removal. The key components of mucus are glycoproteins which are also known as mucins. Mucins are currently defined as proteins whose mass consists 50% or more of O-linked oligosaccharides. There are two forms of mucins , membrane-associated mucins and secreted mucins. The two forms vary in their structure and their function. Membrane-associated mucins are hydrophobic and therefore do not form oligomeric complexes. However, secreted mucins , also known as gel-forming mucins , are commonly found in oligomeric complexes with molecular weights greater than 40 million Daltons. Subunits in these oligomers are linked to one another via disulfide bonds. Secreted mucins give mucus its sticky consistency and help it to serve as a first line of defense in the body. While membrane-associated and secreted mucins vary in both structure and function , they share several common structural features . MUC7 is small secreted mucin , which exists solely as a monomer, and it is predominately expressed in the submandibular and sublingual glands. It has different functions, both immune and non-immune. It is thought that MUC7 may exist in other oral tissues to perform similar functions or different ones. Thus the aim of this study is to investigate the validity of this hypothesis.en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.rightsThis work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.en_US
dc.subjectMUC7 protein, humanen_US
dc.titleExplorative investigation of MUC7 expression in oral tissuesen_US
dc.typeThesis/Dissertationen_US
etd.degree.nameMaster of Science in Dentistryen_US
etd.degree.levelmastersen_US
etd.degree.disciplineProsthodonticsen_US
etd.degree.grantorBoston Universityen_US
dc.identifier.mmsid99193449480001161


This item appears in the following Collection(s)

Show simple item record