Effect of fluoride on the calcification of allogenic bone implants in rats
Brown, Marvin L.
Burdine, John T.
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In twenty-five (25) male adult rats which had decalcified allogenic bone implants placed in mid-fibular gaps and kept on a low-fluoride casein diet (1 ppm- fluoride), the addition of 25 p.p.m. fluoride to the drinking water did not show any direct detectable relationship to the mg % calcium in the ashed implants or in ashed adjacent tibial bone, nor in the percent ash content. Neither did the fluoride enhance or inhibit the success of the implants. For all implants did calcify and only one control mid-fibular gap closed on its own. It is our conclusion that fluoride at levels used in this experiment have no effect on calcification of allogenic bone implants.
Thesis (M.Sc.D.)--Boston University School of Graduate Dentistry, 1974. Periodontics.Bibliography included.
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