A clinical and experimental study of jet injections
ElGeneidy, Ahmed K.
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Since the jet injection was clinically introduced in 1947, little work has been done to evaluate the tissue response to the technique. The present investigation compares the tissue reaction of the jet injections to that of needle injections. The animal investigation was carried out on 30 adult rats, divided into four groups, using a tuberculin syringe with a 26 gauge needle on the control side and a Syrijet Mark II on the experimental. The first group of 18 rats was injected with saline and sacrificed two at a time immediately and at one, two, three, four, six, twelve, twenty-four and forty-eight hours. The second group of eight rats was injected with saline and sacrificed one at a time at two, three, four, six, twelve, twenty-four and forty-eight hours. Prior to sacrifice this group received intraperitoneal injections of trypan blue at half-hourly intervals for a total of three injections and was sacrificed half an hour after the last injection. The third group of two rats received trypan blue injections instead of saline and were sacrificed immediately. The fourth group of two rats was injected with India ink and sacrificed immediately. Stereoscopic and histological examination revealed that injected solutions invariably follow the lines of least resistance in the connective tissues and muscles. Both techniques demonstrate areas of hemorrhage and disruption of connective tissue fibres and displacement of epithelial cells into the underlying connective tissues. An acute inflammatory reaction and damaged connective tissue and muscle fibres was observed following injection techniques. Resolution was rooted in most cases within 48 hours.
PLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please click Download and log in with a valid BU account to access. If you are the author of this work and would like to make it publicly available, please contact firstname.lastname@example.org.Thesis (M.Sc.D.)--Boston University School of Graduate Dentistry, 1973. Oral Biology.Bibliography included.
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