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dc.contributor.authorBraverman, Eric R.en_US
dc.contributor.authorChen, Amanda Lih-Chuanen_US
dc.contributor.authorChen, Thomas J. H.en_US
dc.contributor.authorSchoolfield, John Den_US
dc.contributor.authorNotaro, Alisonen_US
dc.contributor.authorBraverman, Dashaen_US
dc.contributor.authorKerner, Malloryen_US
dc.contributor.authorBlum, Seth H.en_US
dc.contributor.authorArcuri, Vanessaen_US
dc.contributor.authorVarshavskiy, Michaelen_US
dc.contributor.authorDamle, Umaen_US
dc.contributor.authorDowns, B. Williamen_US
dc.contributor.authorWaite, Roger L.en_US
dc.contributor.authorOscar-Berman, Marleneen_US
dc.contributor.authorGiordano, Johnen_US
dc.contributor.authorBlum, Kennethen_US
dc.date.accessioned2012-01-11T21:07:27Z
dc.date.available2012-01-11T21:07:27Z
dc.date.issued2010-10-15
dc.identifier.citationBraverman, Eric R, Amanda Lih-Chuan Chen, Thomas JH Chen, John D Schoolfield, Alison Notaro, Dasha Braverman, Mallory Kerner, Seth H Blum, Vanessa Arcuri, Michael Varshavskiy, Uma Damle, B William Downs, Roger L Waite, Marlene Oscar-Berman, John Giordano, Kenneth Blum. "Test of variables of attention (TOVA) as a predictor of early attention complaints, an antecedent to dementia" Neuropsychiatric Disease and Treatment 6: 681-690. (2010)
dc.identifier.issn1178-2021
dc.identifier.urihttps://hdl.handle.net/2144/3181
dc.description.abstractThe goal of this study was to determine if impairments detected by the test of variables of attention (TOVA) may be used to predict early attention complaints and memory impairments accurately in a clinical setting. We performed a statistical analysis of outcomes in a patient population screened for attention deficit hyperactivity disorder or attention complaints, processing errors as measured by TOVA and the Wechsler Memory Scale (WMS-III) results. Attention deficit disorder (ADD) checklists, constructed using the Diagnostic and Statistical Manual of Mental Disorders 4th Edition criteria, which were completed by patients at PATH Medical, revealed that 72.8% of the patients had more than one attention complaint out of a total of 16 complaints, and 41.5% had more than five complaints. For the 128 males with a significant number of ADD complaints, individuals whose scores were significantly deviant or borderline (SDB) on TOVA, had a significantly greater number of attention complaints compared with normals for omissions (P > 0.02), response time (P > 0.015), and variability (P > 0.005), but not commissions (P < 0.50). For males, the mean scores for auditory, visual, immediate, and working memory scores as measured by the WMS-III were significantly greater for normals versus SDBs on the TOVA subtest, ie, omission (P > 0.01) and response time (P > 0.05), but not variability or commissions. The means for auditory, visual, and immediate memory scores were significantly greater for normals versus SDBs for variability (P > 0.045) only. In females, the mean scores for visual and working memory scores were significantly greater for normals versus SDBs for omissions (P > 0.025). The number of SDB TOVA quarters was a significant predictor for "impaired" or "normal" group membership for visual memory (P > 0.015), but not for the other three WMS-III components. For males, the partial correlation between the number of attention complaints and the number of SDB TOVA quarters was also significant (r = 0.251, P > 0.005). For the 152 females with a significant number of attention complaints, no significant differences between SDBs and normals were observed (P < 0.15). This is the first report, to our knowledge, which provides evidence that TOVA is an accurate predictor of early attention complaints and memory impairments in a clinical setting. This finding is more robust for males than for females between the ages of 40 and 90 years.en_US
dc.language.isoen
dc.publisherDove Medical Pressen_US
dc.rightsCopyright 2010 Braverman et al, publisher and licensee Dove Medical Press Ltd.en_US
dc.subjectAttention complaintsen_US
dc.subjectDementiaen_US
dc.subjectTOVAen_US
dc.subjectWechsler Memory Scaleen_US
dc.titleTest of Variables of Attention (TOVA) as a Predictor of Early Attention Complaints, an Antecedent to Dementiaen_US
dc.typeArticleen_US
dc.identifier.doi10.2147/NDT.S12243
dc.identifier.pmid21127685
dc.identifier.pmcid2987500


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