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dc.contributor.advisorHadland, Scotten_US
dc.contributor.authorOlsen, Andrew Edwarden_US
dc.date.accessioned2019-01-09T14:25:12Z
dc.date.available2019-01-09T14:25:12Z
dc.date.issued2018
dc.identifier.urihttps://hdl.handle.net/2144/33025
dc.description.abstractSupervised Injection Facilities (SIFs) for the medical supervision of illicit drug use exist in Europe, Canada, and Australia to reduce infectious disease transmission, overdose deaths, and other harms of drug use. They have been shown to reduce rates of needle sharing by 69% and local overdose mortality by 35% without increasing rates of drug use or related crime. In light of increasing rates of illicit opioid use and overdose death in Massachusetts, the Massachusetts Medical Society recently endorsed opening a SIF in Boston. This thesis proposes a study of the Boston SIF with the hypothesis that higher SIF utilization will be associated with decreased incidence of fatal overdose, HIV seroconversion, and HCV seroconversion during the study period. I propose evaluating this hypothesis prospectively by following clients of the SIF at 6 month intervals and comparing the rates of overdose death and HIV or HCV seroconversion among frequent and infrequent clients of the SIF. Based on data reported from previous SIFs and projections of the population of people who inject drugs (PWID) in Boston, a study with this design should detect a significant difference in these three primary endpoints between people using the SIF frequently and those using it infrequently within five years. A positive finding would confirm the efficacy of SIFs in harm reduction and secondary prevention for Opioid Use Disorder (OUD), potentially leading to broader adoption in other hotspots of opioid use in the United States.en_US
dc.language.isoen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectMedicineen_US
dc.subjectAddictionen_US
dc.subjectOUDen_US
dc.subjectSIFen_US
dc.subjectDrug consumption roomen_US
dc.subjectOpioid use disorderen_US
dc.subjectSupervised injection facilityen_US
dc.titleA proposed study of supervised injection on Boston's "Recovery Road"en_US
dc.typeThesis/Dissertationen_US
dc.date.updated2018-10-25T19:03:19Z
etd.degree.nameMaster of Scienceen_US
etd.degree.levelmastersen_US
etd.degree.disciplinePhysician Assistant Programen_US
etd.degree.grantorBoston Universityen_US


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International