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dc.contributor.authorSteele, Stephanie Jarvien_US
dc.contributor.authorFarchione, Todd J.en_US
dc.contributor.authorCassiello-Robbins, Clairen_US
dc.contributor.authorAmetaj, Amandaen_US
dc.contributor.authorSbi, Sophiaen_US
dc.contributor.authorSauer-Zavala, Shannonen_US
dc.contributor.authorBarlow, David H.en_US
dc.date.accessioned2019-02-28T14:38:49Z
dc.date.available2019-02-28T14:38:49Z
dc.date.issued2018-09-01
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000443788300031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=6e74115fe3da270499c3d65c9b17d654
dc.identifier.citationStephanie Jarvi Steele, Todd J Farchione, Clair Cassiello-Robbins, Amanda Ametaj, Sophia Sbi, Shannon Sauer-Zavala, David H Barlow. 2018. "Efficacy of the Unified Protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disorders." JOURNAL OF PSYCHIATRIC RESEARCH, Volume 104, pp. 211 - 216 (6). https://doi.org/10.1016/j.jpsychires.2018.08.005
dc.identifier.issn0022-3956
dc.identifier.issn1879-1379
dc.identifier.urihttps://hdl.handle.net/2144/33649
dc.description.abstractOBJECTIVE: This study aimed to examine whether the Unified Protocol (UP), a transdiagnostic cognitive-behavioral therapy for emotional disorders (i.e., anxiety, mood, and related disorders), is efficacious in the treatment of co-occurring emotional disorders compared to established single disorder protocols (SDPs) that target specific disorders (e.g., panic disorder). METHOD: Participants included 179 adults seeking outpatient psychotherapy. Participant age ranged from 18 to 66 years, with an average of 30.66 years (SD = 10.77). The sample was 55% female and mostly Caucasian (83%). Diagnostic assessments were completed with the Anxiety Disorder Interview Schedule (ADIS), and disorder-specific, clinician-rated measures for the comorbid diagnoses of interest. RESULTS: In both treatment conditions, participants' mean number of diagnoses dropped significantly from baseline to posttreatment, and baseline to 12-month follow-up. Additionally, large effects were observed for changes in comorbid generalized anxiety (ES𝐬ɢ: UP = −1.72; SDP = −1.98), social anxiety (ES𝐬ɢ: UP = −1.33, −0.86; SDP = −1.60, −1.54), and depression (ES𝐬ɢ: UP = −0.83; SDP = −0.84). Significant differences were not observed in between-group comparisons. CONCLUSIONS: Results suggest that both the UP and SDPs are efficacious in reducing symptoms of comorbid emotional disorders. The clinical, practical, and cost-effective advantages of transdiagnostic CBT are discussed.en_US
dc.description.sponsorshipPlease note the following financial disclosures/conflicts of interest: Dr. Barlow reported receiving royalties from Oxford University Press, United Kingdom (which includes royalties for the treatment manuals included in this study); Guilford Publications Inc., United States; Cengage Learning, United States; Pearson Publishing, United Kingdom. He reported receiving grants from the National Institute of Mental Health, United States (R01 MH090053) and the National Institute of Alcohol and Alcohol Abuse, United States (R01 AA023676). He reported serving as a consultant for and receiving honoraria from the Agency for Healthcare Research and Quality, United States; the Foundation for Informed Medical Decision Making, United States; the Department of Defense, United States; the Renfrew Center, United States; the Chinese University of Hong Kong, Hong Kong;Universidad Catolica de Santa Maria, Peru); New Zealand Psychological Association, New Zealand; Hebrew University of Jerusalem, Israel; Mayo Clinic, United States; and various American universities. (R01 MH090053 - National Institute of Mental Health, United States; R01 AA023676 - National Institute of Alcohol and Alcohol Abuse, United States)en_US
dc.format.extentp. 211 - 216en_US
dc.languageEnglish
dc.language.isoen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.relation.ispartofJournal of Psychiatric Research
dc.subjectScience & technologyen_US
dc.subjectLife sciences & biomedicineen_US
dc.subjectPsychiatryen_US
dc.subjectUnified protocolen_US
dc.subjectCognitive behavioral therapyen_US
dc.subjectTransdiagnostic treatmenten_US
dc.subjectComorbidityen_US
dc.subjectEmotional disordersen_US
dc.subjectRandomized controlled trialen_US
dc.subjectObsessive-compulsive scaleen_US
dc.subjectStructured interview guideen_US
dc.subjectSocial anxiety scaleen_US
dc.subjectDSM-IV anxietyen_US
dc.subjectPanic disorderen_US
dc.subjectPsychometric propertiesen_US
dc.subjectSeverity scaleen_US
dc.subjectRating-scaleen_US
dc.subjectMood disordersen_US
dc.subjectTransdiagnostic treatmenten_US
dc.subjectMedical and health sciencesen_US
dc.subjectPsychology and cognitive sciencesen_US
dc.subjectPsychiatryen_US
dc.titleEfficacy of the Unified Protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disordersen_US
dc.typeArticleen_US
dc.description.versionAccepted manuscripten_US
dc.identifier.doi10.1016/j.jpsychires.2018.08.005
pubs.elements-sourceweb-of-scienceen_US
pubs.notesEmbargo: No embargoen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, Administrationen_US
pubs.organisational-groupBoston University, College of Arts & Sciencesen_US
pubs.organisational-groupBoston University, College of Arts & Sciences, Department of Psychological & Brain Sciencesen_US
pubs.publication-statusPublisheden_US


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