Boston University Libraries OpenBU
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    •   OpenBU
    • Centers & Institutes
    • Pulmonary Center
    • Pulmonary Center Papers
    • View Item
    •   OpenBU
    • Centers & Institutes
    • Pulmonary Center
    • Pulmonary Center Papers
    • View Item

    Growth Factors in Lung Development and Disease: Friends or Foe?

    Thumbnail
    Date Issued
    2001-10-9
    Publisher Version
    10.1186/rr169
    Author(s)
    Desai, Tushar J.
    Cardoso, Wellington V.
    Share to FacebookShare to TwitterShare by Email
    Export Citation
    Download to BibTex
    Download to EndNote/RefMan (RIS)
    Metadata
    Show full item record
    Permanent Link
    https://hdl.handle.net/2144/3395
    Citation (published version)
    Desai, Tushar J, Wellington V Cardoso. "Growth factors in lung development and disease: friends or foe?" Respiratory Research 3(1):2. (2001)
    Abstract
    Growth factors mediate tissue interactions and regulate a variety of cellular functions that are critical for normal lung development and homeostasis. Besides their involvement in lung pattern formation, growth and cell differentiation during organogenesis, these factors have been also implicated in modulating injury-repair responses of the adult lung. Altered expression of growth factors, such as transforming growth factor β1, vascular endothelial growth factor and epidermal growth factor, and/or their receptors, has been found in a number of pathological lung conditions. In this paper, we discuss the dual role of these molecules in mediating beneficial feedback responses or responses that can further damage lung integrity; we shall also discuss the basis for their prospective use as therapeutic agents.
    Rights
    Copyright 2001 BioMed Central Ltd
    Collections
    • Pulmonary Center Papers [21]


    Boston University
    Contact Us | Send Feedback | Help
     

     

    Browse

    All of OpenBUCommunities & CollectionsIssue DateAuthorsTitlesSubjectsThis CollectionIssue DateAuthorsTitlesSubjects

    Deposit Materials

    LoginNon-BU Registration

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Boston University
    Contact Us | Send Feedback | Help