High Density Lipoproteins-Based Therapies for Cardiovascular Disease
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CitationGao, Xuan, Shujun Yuan. "High density lipoproteins-based therapies for cardiovascular disease" Journal of Cardiovascular Disease Research 1(3): 99-103. (2010)
Atherosclerosis is the leading cause of death in developed countries. High density lipoproteins (HDL) cholesterol level correlates inversely with the risk of cardiovascular diseases. Thus, HDL has obtained lots of interest for drug development. In this review, we summarized the mechanisms for the antiatherogenic function of HDL, current HDL-based drugs in clinical use and the future direction for HDL-based therapy development.