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dc.contributor.authorAppleman, E. R.en_US
dc.contributor.authorStavitsky, K.en_US
dc.contributor.authorCronin-Golomb, Aliceen_US
dc.date.accessioned2019-03-27T15:31:25Z
dc.date.available2019-03-27T15:31:25Z
dc.date.issued2011
dc.identifier.citationER Appleman, K Stavitsky, A Cronin-Golomb. 2011. "Relation of subjective quality of life to motor symptom profile in Parkinson's disease." Parkinson’s Disease, Volume 2011, https://doi.org/10.4061/2011/472830
dc.identifier.urihttps://hdl.handle.net/2144/34367
dc.description.abstractParkinson's disease (PD) presents with extensive heterogeneity in symptomatology, inviting examination of disease subtypes. One significant categorization is by whether patients present at onset with tremor as the dominant symptom (TD) or with nontremor symptoms (NTD). We examined differences in quality of life between TD and NTD patients using the Parkinson's Disease Questionnaire-39 (PDQ-39), correlating performance with aspects of motor function as indexed by the Unified Parkinson's Disease Rating Scale (UPDRS). Participants included 35 nondemented individuals (19 TD, 16 NTD) matched on clinical and demographic characteristics. NTD had significantly lower overall PDQ-39 scores, particularly for the mobility subscale. Several UPDRS subscale scores significantly correlated with quality of life, especially for NTD. Further, the correlations were driven by nontremor type symptoms, even in TD patients. Determining reliable subtypes of PD may aid in prognosis and treatment optimization, thereby enhancing quality of life in afflicted individuals.en_US
dc.language.isoen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.ispartofParkinson’s Disease
dc.rightsAttribution 4.0 Internationalen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectScience & technologyen_US
dc.subjectLife sciences & biomedicineen_US
dc.subjectClinical neurologyen_US
dc.subjectNeurosciences & neurologyen_US
dc.titleRelation of subjective quality of life to motor symptom profile in Parkinson's diseaseen_US
dc.typeArticleen_US
dc.description.versionPublished versionen_US
dc.identifier.doi10.4061/2011/472830
pubs.elements-sourcemanual-entryen_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Arts & Sciencesen_US
pubs.organisational-groupBoston University, College of Arts & Sciences, Department of Psychological & Brain Sciencesen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0001-5699-6204 (Cronin-Golomb, A)


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Except where otherwise noted, this item's license is described as Attribution 4.0 International