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dc.contributor.authorReynolds, Gretchen O.en_US
dc.contributor.authorHanna, Kristine K.en_US
dc.contributor.authorNeargarder, Sandyen_US
dc.contributor.authorCronin-Golomb, Aliceen_US
dc.date.accessioned2019-03-29T14:35:40Z
dc.date.available2019-03-29T14:35:40Z
dc.date.issued2017-09-01
dc.identifier.citationGO Reynolds, KK Hanna, S Neargarder, A Cronin-Golomb. 2017. "The relation of anxiety and cognition in Parkinson's disease." Neuropsychology, Volume 31, Issue 6, pp. 596 - 604. https://doi.org/10.1037/neu0000353
dc.identifier.issn0894-4105
dc.identifier.urihttps://hdl.handle.net/2144/34381
dc.description.abstractOBJECTIVE: Parkinson’s disease (PD) has long been conceptualized as a motor disorder, but nonmotor symptoms also manifest in the disease and significantly reduce quality of life. Anxiety and cognitive dysfunction are prevalent nonmotor symptoms, even in early disease stages, but the relation between these symptoms remains poorly understood. We examined self-reported anxiety and neurocognitive function, indexed by measures of executive function (set-shifting and phonemic fluency), categorical fluency, and attention/working memory. We hypothesized that anxiety would correlate with cognitive performance. METHOD: The Beck Anxiety Inventory and cognitive tests (Trail Making, Verbal Fluency, Digit Span) were administered to 77 nondemented adults with mild to moderate idiopathic PD (39 men, 38 women; Mage = 62.9 years). RESULTS: Higher anxiety was associated with more advanced disease stage and severity and with poorer set-shifting when using a derived metric to account for motoric slowing. Depression correlated with greater anxiety and disease severity, but not with cognitive performance. CONCLUSIONS: Our findings support the association of anxiety with a specific domain of executive function, set-shifting, in nondemented individuals with mild to moderate PD, raising the possibility that treatment of anxiety may alleviate aspects of executive dysfunction in this population.en_US
dc.format.extentp. 596 - 604en_US
dc.language.isoen_US
dc.publisherAmerican Psychological Associationen_US
dc.relation.ispartofNeuropsychology
dc.subjectPsychologyen_US
dc.subjectNeurosciencesen_US
dc.subjectExperimental psychologyen_US
dc.titleThe relation of anxiety and cognition in Parkinson's diseaseen_US
dc.typeArticleen_US
dc.description.versionAccepted manuscripten_US
dc.identifier.doi10.1037/neu0000353
pubs.elements-sourcemanual-entryen_US
pubs.notesEmbargo: No embargoen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Arts & Sciencesen_US
pubs.organisational-groupBoston University, College of Arts & Sciences, Department of Psychological & Brain Sciencesen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0001-5699-6204 (Cronin-Golomb, A)


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