The effect of dental caries on the human pulp: a correlation of clinical and histopathological observations
Peikoff, Marshall D.
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The purpose of this study was initially to devise an easily reproducible method of attaining accurate histologic sections of the dental pulp and its surrounding dentin. Upon accomplishing this, teeth with carles at various depths were examined clinically, extracted, studied histologically, and the resultant pulpal response described. An attempt was then made at correlating clinical findings with histopathologic observations. When caries first penetrates the peripheral dentin, a pulpal response was demonstrated which included a reduction in the odontoblastic layer, a localized inflammatory infiltrate and dilatation of capillaries in the affected area generally, the pulpal response was more severe as the carles penetrated deeper, being most severe upon pulpal exposure. A fairly consistently accurate correlation was shown to exist between clinical and histopathologic findings in carious human teeth, although further study is required to substantiate these observations.
Thesis (M.Sc.D.)--Boston University, School of Graduate Dentristry, 1969.Bibliography, colored photographs, tables included.
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