A versatile low-cost microcontroller-based 4-channel potentiostat platform for electrochemical biosensor development
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Electrochemical biosensors provide high specificity of analyte detection in different body fluids. A potentiostat is the instrument used to control the applied potential and measure current flow in the electrochemical cell, where the analyte detection reaction occurs. Advances in electronics and microcontrollers have enabled such sophisticated instruments to be built at a very low cost with sufficient performance. We report the analysis, design, and prototyping of a low-cost 4-channel potentiostat that is fully integrated into one PCB connected to an Arduino Uno board, as an Arduino shield, which could be used for both biosensor development and applications. As an Arduino-based instrument, the MATLAB-based software of the potentiostat is relatively easily modified for different biosensor requirements, providing great versatility for end users. We believe that this design will be valuable for electrochemical biosensors researchers as well as students interested in electrochemistry. The reported low-cost architecture could also be adopted to create low-cost diagnostic instruments for resource-limited settings.
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