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dc.contributor.authorMcIntyre, Daviden_US
dc.contributor.authorDensmore, Douglasen_US
dc.date.accessioned2019-07-31T12:50:46Z
dc.date.available2019-07-31T12:50:46Z
dc.date.issued2019-07
dc.identifier.citationD. McIntyre, D. Densmore. (2019). Design Automation of Microfluidic Droplet Sorting Platforms. In The Proceedings of the 11th International Workshop on Bio-Design Automation (IWBDA-19).
dc.identifier.urihttps://hdl.handle.net/2144/36719
dc.description.abstractBoth basic research and biological design require high throughput screening to parse through the massive amounts of variants generated in experiments. However, the cost and expertise needed for use of such technology limit accessibility. Simple and reproducible designs of a sorting platform would reduce the barrier for implementation of affordable bench-top screening platforms. Droplet microfluidics present a promising approach for automating biology, reducing reaction volumes to picoliter droplets and allowing for deterministic manipulation of samples. Droplet microfluidics have been used extensively for high throughput screening and directed evolution, yet limitations in fabrication have prevented the characterization needed for a design tool and subsequent widespread adoption. Here, we present a finite element analysis (FEA) model-based design framework for dielectrophoretic droplet microfluidic sorters and its preliminary experimental validation. This framework extends previous work from our group creating microfluidic designs tools, increasing their usability in the lab.en_US
dc.language.isoen_US
dc.publisher11th International Workshop on Bio-Design Automation (IWBDA-19)en_US
dc.subjectMicrofluidicsen_US
dc.subjectAutomationen_US
dc.titleDesign automation of microfluidic droplet sorting platformsen_US
dc.typeConference materialsen_US


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