Development and characterization of a multidistance and multiwavelength diffuse correlation spectroscopy system
Boas, David A.
Franceschini, Maria Angela
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Citation (published version)Davide Tamborini, Parisa Farzam, Bernhard Zimmermann, Kuan-Cheng Wu, David A. Boas, Maria Angela Franceschini, “Development and characterization of a multidistance and multiwavelength diffuse correlation spectroscopy system,” Neurophoton. 5(1), 011015 (2017), https://doi.org/10.1117/1.NPh.5.1.011015
This paper presents a multidistance and multiwavelength diffuse correlation spectroscopy (DCS) approach and its implementation to simultaneously measure the optical proprieties of deep tissue as well as the blood flow. The system consists of three long coherence length lasers at different wavelengths in the near-infrared, eight single-photon detectors, and a correlator board. With this approach, we collect both light intensity and DCS data at multiple distances and multiple wavelengths, which provide unique information to fit for all the parameters of interest: scattering, blood flow, and hemoglobin concentration. We present the characterization of the system and its validation with phantom measurements.
Rights© The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.NPh.5.1.011015]