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dc.contributor.authorDaneshvar, Daniel H.en_US
dc.date.accessioned2019-09-26T14:46:41Z
dc.date.issued2007
dc.date.submitted2007
dc.identifier.otherb27236821
dc.identifier.urihttps://hdl.handle.net/2144/38021
dc.descriptionThesis (M.A.)--Boston Universityen_US
dc.descriptionPLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.en_US
dc.description.abstractIncreasing evidence indicates that the sooner treatment begins for patients with Alzheimer's Disease (AD), the better the chance of delaying progression of the disease. As a result, studies have begun focusing on risk factors for AD with the goal of identifying individuals with AD at the earliest possible stage. Such studies have found that individuals with Mild Cognitive Impairment (MCI) are at increased risk for AD and other forms of dementia. This study examines the potential mediating effect of a set of prospective risk factors, smoking and ApolipoproteinE (ApoE) genotype, on the incidence of MCI and AD. Although results of this study provide some preliminary evidence of an interaction, the study models presented here fail to reach significance. Additional studies are needed to confirm the hypothesis of an ApoE mediated relationship of smoking on MCI and AD.en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectSmokingen_US
dc.subjectRisk factorsen_US
dc.subjectApolipoprotein Een_US
dc.titleAn apolipoprotein-E mediated relationship between smoking and risk of mild cognitive impairment and Alzheimer's diseaseen_US
dc.typeThesis/Dissertationen_US
dc.description.embargo2031-01-01
etd.degree.nameMaster of Artsen_US
etd.degree.levelmastersen_US
etd.degree.disciplineMedical Sciencesen_US
etd.degree.grantorBoston Universityen_US
dc.identifier.barcode11719022885687
dc.identifier.mmsid99183050920001161


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