Eucalyptusdimers A-C, dimeric phloroglucinol phellandrene meroterpenoids from Eucalyptus robusta
Porco, John A.
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Citation (published version)Xu-Jie Qin, Mi-Yan Feng, Hui Liu, Wei Ni, Tyler Rauwolf, John A Porco, Huan Yan, Li He, Hai-Yang Liu. 2018. "Eucalyptusdimers A-C, Dimeric Phloroglucinol Phellandrene Meroterpenoids from Eucalyptus robusta." ORGANIC LETTERS, Volume 20, Issue 16, pp. 5066 - 5070. https://doi.org/10.1021/acs.orglett.8b02259
Eucalyptusdimers A–C, three dimeric phellandrene-derived meroterpenoids featuring an unprecedented, fused skeleton between two phellandrene and two acylphloroglucinol subunits, along with one biogenetically related intermediate, (±)-eucalyprobusone A, were isolated from the fruits of Eucalyptus robusta. Their structures and absolute configurations were elucidated using spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. The isolated meroterpenoids were evaluated for their anti-inflammatory, acetylcholinesterase inhibitory, and protein tyrosine phosphatase 1B inhibitory effects.
Published in final edited form as: Org Lett. 2018 August 17; 20(16): 5066–5070. doi:10.1021/acs.orglett.8b02259.