Show simple item record

dc.contributor.advisorOffner, Gwynnethen_US
dc.contributor.advisorStearns-Kurosawa, Deborah J.en_US
dc.contributor.authorChawla, Drishtien_US
dc.date.accessioned2019-11-27T16:15:06Z
dc.date.available2019-11-27T16:15:06Z
dc.date.issued2019
dc.identifier.urihttps://hdl.handle.net/2144/38604
dc.description.abstractThe human vagina is unlike that of any closely related phylogenetic species due to the abundance of a lactic acid producing bacteria, known as Lactobacillus. This microbial species is known for its direct and indirect contributions to vaginal pathogenic defense, some of which include the elicitation of host immunomodulators, release of bacteriocins and biosurfactants, and lowering of vaginal pH. While Lactobacillus is often considered the hallmark of a healthy human vagina, a significant number of women worldwide lack its abundance in their vaginal microbial communities. The lack of Lactobacillus- dominance does not necessarily equate to a disease-state but could potentially explain an increased risk of viral transmission and recurrent vaginal dysbiosis in these women. This thesis aims to investigate the numerous antimicrobial properties associated with the Lactobacillus species to better understand its significance for female reproductive and vaginal health.en_US
dc.language.isoen_US
dc.subjectMicrobiologyen_US
dc.subjectBacterial vaginosisen_US
dc.subjectLactobacillusen_US
dc.subjectMicrobiomeen_US
dc.subjectVaginaen_US
dc.subjectWomen's healthen_US
dc.titleThe distinct role of the Lactobacillus species in maintenance of vaginal eubiosisen_US
dc.typeThesis/Dissertationen_US
dc.date.updated2019-10-09T16:03:23Z
etd.degree.nameMaster of Scienceen_US
etd.degree.levelmastersen_US
etd.degree.disciplineMedical Sciencesen_US
etd.degree.grantorBoston Universityen_US


This item appears in the following Collection(s)

Show simple item record