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dc.contributor.authorBhambra, Jhujhar S.en_US
dc.date.accessioned2019-12-10T14:06:26Z
dc.date.available2019-12-10T14:06:26Z
dc.date.issued2006
dc.date.submitted2006
dc.identifier.other(OCoLC)155045298
dc.identifier.other(OCoLC)155045298
dc.identifier.otherb27364884
dc.identifier.urihttps://hdl.handle.net/2144/38704
dc.descriptionThesis (MSD)--Boston University Goldman School of Dental Medicine, 2006 (Endodontics).en_US
dc.descriptionIncludes bibliography: leaves 92-102.en_US
dc.description.abstractThe hypothesis of this study was that [Ca2+] and [Si4+] ions might dissolve from Mineral Trioxide Aggregate (MTA) which enhances hard tissue formation. The purpose of this experiment was to determine the dissolution of [Ca2+] and [Si4+] ions from MTA into culture medium and to determine if this dissolution could be altered by adding 1) 6% Silicon and 4.5% Calcium and 2) 30% Silicon to MTA to yield 2 modified versions, mMTA1 and mMTA2 respectively. Discs (15.6 mm diameter X 2 mm) of MTA, mMTA1, and mMTA2 were prepared and placed into 24 well plates to which 1.5ml of culture medium was added and incubated at 37C, 5% CO2 and 100% humidity. The culture medium was changed, collected, and pH readings were taken every 3-4 days for 15, 30, 60 and 90 day intervals. The [Ca2+] and [Si4+] in the culture medium were analyzed using inductively coupled plasma. The pH readings of the culture medium were not significantly different among the control, MTA, mMTA1 and mMTA2. Using ANOVA and Tukey HSD statistics mMTA1 leached more [Si4+] than MTA and mMTA2 with statistical significance (p[less than]0.05) at all time intervals. MTA and mMTA1 leached more calcium than mMTA2 (p[less than]0.05) at 90 days but no differences were seen among MTA, mMTA1 and mMTA2 at other time intervals. In conclusion, [Ca2+] and [Si4+] dissolves from MTA into culture medium. This dissolution of [Ca2+] and [Si4+] can be modified with the addition of Silicon. Funding by Boston University Departments of Endodontics and Biomaterials.en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.rightsThis work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author.en_US
dc.subjectCalciumen_US
dc.subjectMineral trioxide aggregateen_US
dc.subjectSiliconen_US
dc.titleThe dissolution of calcium and silicon ions from mineral trioxide aggregate (MTA) and two modified versions of MTA in culture mediumen_US
dc.typeThesis/Dissertationen_US
etd.degree.nameMaster of Science in Dentistryen_US
etd.degree.levelmastersen_US
etd.degree.disciplineEndodonticsen_US
etd.degree.grantorBoston Universityen_US


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