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dc.contributor.authorGhattas, Mazen Souhailen_US
dc.date.accessioned2019-12-10T14:10:06Z
dc.date.available2019-12-10T14:10:06Z
dc.date.issued2010
dc.date.submitted2010
dc.identifier.other(OCoLC)752324542
dc.identifier.other(OCoLC)752324542
dc.identifier.otherb36998114
dc.identifier.urihttps://hdl.handle.net/2144/38714
dc.descriptionDissertation (MSD) --Boston University, Henry M. Goldman School of Dental Medicine, 2010 (Department of Periodontology and Oral Biology).en_US
dc.descriptionIncludes bibliographic references: leaves 93-109.en_US
dc.description.abstractAlthough immediate implant placement has been demonstrated to be as reliable as traditional surgical techniques, several problems relating to primary stability, consistent management of soft tissue, and bone healing on implant surfaces at the coronal level where a wide gap between bone and implant was present at the implantation time, have been reported. The search for suitable bone substitute materials has intensified over the years due to the shortcomings of autografts, mainly donor site morbidity and limited available bone volume. The aim of the present “proof of concept study” was to evaluate the impact of light/chemically hardened poly-methyl-methacrylate, poly-ethyl-methacrylate and calcium hydroxide composite graft in combination with polyanhydride (PPCH + PA) on immediate implant stability and function and the ability to augment extraction sockets in a mini-pig model. Four mandibular premolar teeth and one molar tooth per quadrant were extracted; a total of 48 implants and 60 sockets were randomly assigned to receive one of the four treatments: 1) augmentation with PPCH + PA; 2) augmentation with PA; 3) augmentation with PPCH and 4) no augmentation. At 12 weeks, block sections were obtained. Implant stability was measured using Periotron at 2, 6 and 12 weeks. Soft tissue probing, and radiological evaluations were performed to detect any soft tissue reaction and bone resorption around implants. Implant-bone interface was examined with mechanical test using lnstron followed by a scanning electron microscope evaluations, microcomputed tomography (microCT) and histopathological evaluations. The resected blocks were demineralized, and stained with either hematoxylin and eosin or Masson’s trichrome for evaluation of bone and collagen formation and histomorphometric measurements. The results of the present study demonstrate that socket preservation and augmentation of implants after immediate implant placement promoted bone formation and supported the stability of the implants. [TRUNCATED]en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.rightsThis work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author.en_US
dc.subjectDental materialsen_US
dc.subjectPolymethyl methacrylateen_US
dc.subjectPolyhydroxyethyl methacrylateen_US
dc.subjectPolyanhydridesen_US
dc.titleThe use of lightchemically-hardened poly-methyl-methacrylate, poly-hydroxy-ethyl-methacrylate and calcium hydroxide graft material in combination with polyanhydride around implants immediately placed into extraction sockets :en_US
dc.typeThesis/Dissertationen_US
etd.degree.nameMaster of Science in Dentistryen_US
etd.degree.levelmastersen_US
etd.degree.disciplinePeriodontology and Oral Biologyen_US
etd.degree.grantorBoston Universityen_US


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