Depression in type 1 diabetic youth: insulin injections vs. pumps
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Type 1 diabetes is an autoimmune disease that involves destruction of pancreatic cells that produce insulin. The disease typically presents in children and adolescents. The burden of disease management, fear of complications, and disruption of normal childhood that the disease causes place youth with type 1 diabetes at increased risk for developing depression compared to peers without the disease. The presence and severity of depression correlates with disease outcomes. Use of continuous subcutaneous insulin infusion pumps has been shown to improve youth’s quality of life compared to use of multiple daily insulin injections. Although quality of life measures are associated with the risk of developing depression, no studies have compared depression symptomatology in youth using insulin pumps to those using multiple daily insulin injections. The proposed project will assess relative depression symptomatology in youth ages 10-17 using insulin pumps and multiple daily insulin injections. The results of this proposed project could help inform clinicians’ decisions about whether to initiate type 1 diabetes therapy in youth with either insulin pumps or insulin injections. Given the financial burden of depression, it could also potentially encourage insurance companies to increase coverage of insulin pumps.