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dc.contributor.advisorBrodeur, Amy N.en_US
dc.contributor.authorWang, Huxien_US
dc.date.accessioned2019-12-11T18:49:13Z
dc.date.available2019-12-11T18:49:13Z
dc.date.issued2019
dc.identifier.urihttps://hdl.handle.net/2144/38738
dc.description.abstractBiological material is a common type of evidence found at a crime scene, and body fluid identification is an essential process in crime scene investigation. One of the most common types of body fluids found is blood. After a stain has been presumptively identified as blood through the use of a colorimetric chemical test, additional testing may be necessary to better characterize the stain. SERATEC PMB Test is a relatively new lateral flow immunochromatographic assay that targets human hemoglobin and D-dimer simultaneously in order to distinguish peripheral blood and menstrual blood at the same time. Elevated levels of D-dimer, a fibrin degradation product, are found in menstrual blood, thrombosis formation and as part of the postmortem process. A previous study investigated levels of D-dimer in menstrual, peripheral and postmortem blood using the SERATEC PMB Test. In this study, all postmortem blood samples showed positive results for both hemoglobin and D-dimer; all peripheral bloodstain samples from living individuals showed positive results for hemoglobin detection, and negative results for D-dimer detection; and most menstrual bloodstain samples showed positive D-dimer results. The results suggest that this assay could be considered a presumptive test for both postmortem blood and menstrual blood. However, as D-dimer concentrations vary between individuals, additional testing is necessary to conclusively distinguish postmortem blood, menstrual blood and peripheral blood from living individuals with especially high D-dimer levels.en_US
dc.language.isoen_US
dc.subjectBiologyen_US
dc.subjectD-dimeren_US
dc.subjectFibrinolysisen_US
dc.subjectForensicsen_US
dc.subjectImmunochromatographic assayen_US
dc.subjectMenstrual blooden_US
dc.subjectPostmortem blooden_US
dc.titleEvaluation of D-dimer in postmortem blood using the SERATEC PMB Testen_US
dc.typeThesis/Dissertationen_US
dc.date.updated2019-11-09T02:01:13Z
etd.degree.nameMaster of Scienceen_US
etd.degree.levelmastersen_US
etd.degree.disciplineBiomedical Forensic Sciencesen_US
etd.degree.grantorBoston Universityen_US
dc.identifier.orcid0000-0002-8707-1375


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