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dc.contributor.authorWalsh, Brian M.en_US
dc.contributor.authorTian, F.en_US
dc.contributor.authorTourville, Jason. A.en_US
dc.contributor.authorYucel, Meryemen_US
dc.contributor.authorKuczek, T.en_US
dc.contributor.authorBostian, A.en_US
dc.date.accessioned2018-02-20T21:08:47Z
dc.date.accessioned2020-01-09T16:03:36Z
dc.date.available2018-02-20T21:08:47Z
dc.date.available2020-01-09T16:03:36Z
dc.date.issued2017-06-22
dc.identifier.citationB. Walsh, F. Tian, J.A. Tourville, M. Yucel, T. Kuczek, A. Bostian. 2017. "Hemodynamics of speech production: An fNIRS investigation of children who stutter.." Scientific Reports, Volume 7, pp. 4034 - 4034. https://doi.org/10.1038/s41598-017-04357-6
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/2144/39059
dc.description.abstractStuttering affects nearly 1% of the population worldwide and often has life-altering negative consequences, including poorer mental health and emotional well-being, and reduced educational and employment achievements. Over two decades of neuroimaging research reveals clear anatomical and physiological differences in the speech neural networks of adults who stutter. However, there have been few neurophysiological investigations of speech production in children who stutter. Using functional near-infrared spectroscopy (fNIRS), we examined hemodynamic responses over neural regions integral to fluent speech production including inferior frontal gyrus, premotor cortex, and superior temporal gyrus during a picture description task. Thirty-two children (16 stuttering and 16 controls) aged 7–11 years participated in the study. We found distinctly different speech-related hemodynamic responses in the group of children who stutter compared to the control group. Whereas controls showed significant activation over left dorsal inferior frontal gyrus and left premotor cortex, children who stutter exhibited deactivation over these left hemisphere regions. This investigation of neural activation during natural, connected speech production in children who stutter demonstrates that in childhood stuttering, atypical functional organization for speech production is present and suggests promise for the use of fNIRS during natural speech production in future research with typical and atypical child populations.en_US
dc.format.extentp. 4034 - 4034en_US
dc.language.isoen_US
dc.publisherNature Publishing Groupen_US
dc.relation.ispartofScientific Reports
dc.relation.replaceshttps://hdl.handle.net/2144/27109
dc.relation.replaces2144/27109
dc.relation.replaces2144/30800
dc.relation.replaceshttps://hdl.handle.net/2144/30800
dc.rightsAttribution 4.0 Internationalen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectScience & technologyen_US
dc.subjectMultidisciplinary sciencesen_US
dc.subjectNear-infrared spectroscopyen_US
dc.subjectTranscranial magnetic stimulationen_US
dc.subjectPositron-emission-tomographyen_US
dc.subjectSuperior temporal gyrusen_US
dc.subjectVoxel-based morphometryen_US
dc.subjectBroca's areaen_US
dc.subjectNeuroanatomical differencesen_US
dc.subjectLanguage productionen_US
dc.subjectSyllable productionen_US
dc.subjectMotor controlen_US
dc.subjectAnalysis of varianceen_US
dc.subjectBiomarkersen_US
dc.subjectBrainen_US
dc.subjectChilden_US
dc.subjectChild, preschoolen_US
dc.subjectFemaleen_US
dc.subjectHemodynamicsen_US
dc.subjectHemoglobinsen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectOxygen consumptionen_US
dc.subjectSpectroscopy, near-infrareden_US
dc.subjectStutteringen_US
dc.subjectBiochemistry and cell biologyen_US
dc.titleHemodynamics of speech production: an fNIRS investigation of children who stutteren_US
dc.typeArticleen_US
dc.identifier.doi10.1038/s41598-017-04357-6
pubs.elements-sourcemanual-entryen_US
pubs.merge-from2144/30800
pubs.merge-fromhttps://hdl.handle.net/2144/30800
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Engineeringen_US
pubs.organisational-groupBoston University, College of Engineering, Department of Biomedical Engineeringen_US
pubs.organisational-groupBoston University, College of Health & Rehabilitation Sciences: Sargent Collegeen_US
pubs.organisational-groupBoston University, College of Health & Rehabilitation Sciences: Sargent College, Speech, Language & Hearing Sciencesen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0002-4291-2847 (Yucel, M)
dc.identifier.mycv239839


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International