Gut microbiota and salivary diagnostics: the mouth is salivating to tell us something.
Faller, Douglas V.
Harpp, David N.
Powers, Whitney R.
Soukos, Nikolaos S.
Moos, Walter H.
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Citation (published version)Krishna Kodukula, Douglas V. Faller, David N. Harpp, Iphigenia Kanara, Julie Pernokas, Mark Pernokas, Whitney R. Powers, Nikolaos S. Soukos, Kosta Steliou, Walter H. Moos. 2017. "Gut Microbiota and Salivary Diagnostics: The Mouth Is Salivating to Tell Us Something.." Biores Open Access, Volume 6, Issue 1, pp. 123 - 132. https://doi.org/10.1089/biores.2017.0020
The microbiome of the human body represents a symbiosis of microbial networks spanning multiple organ systems. Bacteria predominantly represent the diversity of human microbiota, but not to be forgotten are fungi, viruses, and protists. Mounting evidence points to the fact that the "microbial signature" is host-specific and relatively stable over time. As our understanding of the human microbiome and its relationship to the health of the host increases, it is becoming clear that many and perhaps most chronic conditions have a microbial involvement. The oral and gastrointestinal tract microbiome constitutes the bulk of the overall human microbial load, and thus presents unique opportunities for advancing human health prognosis, diagnosis, and therapy development. This review is an attempt to catalog a broad diversity of recent evidence and focus it toward opportunities for prevention and treatment of debilitating illnesses.
RightsCopyright Krishna Kodukula et al. 2017; Published by Mary Ann Liebert, Inc. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.