Pulpal reactions to a glass-ionomer (chembound) in monkeys
Segal, Edith M.
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The glass ionomer cement developed by Wilson and Kent (1971, 1972, 1973) and clinically applied by McLean and Wilson is an extension product resulting from the experiments done with silicates, composite resins, and polycarboxylate cements. The objective was to obtain a material with the combined effect of those components. Recently the De Trey Co. has marketed a glass ionomer cement material, Chembond, for use in cementing crowns, bridges, inlays and onlays. It is claimed that the material is biologically compatible and this, together with the potential for bonding to enamel and dentin, some favorable translucency characteristics, makes it a most outstanding cementing substance. A total of 60 non-carious teeth of three monkeys (cynomolgus fascicularis) were selected. Prior to cavity preparation all surface stains, plaque and calculus were removed by scaling and by cleaning with zircate prophylaxis paste applied with a rubber polishing cup. In each tooth a buccal Class V cavity preparation was performed. The mixed cementing material was inserted and adapted as closely as possible to the margins of the cavity. By studying the animals at one, two and three time intervals it was possible to observe the initial response, the full development of the lesion, and its rate of resolution, thus providing a dynamic sequence of events rather than observing a static situation. The results of the experimental material were related to the effect on the pulp tissue of a positive control material (silicate cement) that has long been condemned as a pulpal irritant, and to a negative control material (a type of zinc oxide-eugenol) that still remains the most effective filling material when prevention of pulpal injury is of prime concern. The biological test showed that this new material produces similar reactions to those produced by zinc oxide eugenol. It means the effects on the pulp were small compared to those found beneath the cavities filled with sili飽te phosphate. The degree of inflammation was confined to the early experimental period probably due to the inevitable inflammation following cavity preparation, but decreased toward the end of the three month interval.
PLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please click Download and log in with a valid BU account to access. If you are the author of this work and would like to make it publicly available, please contact firstname.lastname@example.org.Colored photographs included.Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Graduate Dentistry (Prosthondontics), 1979.Bibliography: leaves 69-78.
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