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dc.contributor.authorFox, Sharon E.en_US
dc.contributor.authorWagner, Jennifer B.en_US
dc.contributor.authorShrock, Christine L.en_US
dc.contributor.authorTager-Flusberg, Helenen_US
dc.contributor.authorNelson, Charles A.en_US
dc.date.accessioned2020-05-06T17:38:05Z
dc.date.available2020-05-06T17:38:05Z
dc.date.issued2013-04-09
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000317335500001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=6e74115fe3da270499c3d65c9b17d654
dc.identifier.citationSharon E Fox, Jennifer B Wagner, Christine L Shrock, Helen Tager-Flusberg, Charles A Nelson. 2013. "Neural processing of facial identity and emotion in infants at high-risk for autism spectrum disorders." FRONTIERS IN HUMAN NEUROSCIENCE, Volume 7, 18 pp. https://doi.org/10.3389/fnhum.2013.00089
dc.identifier.issn1662-5161
dc.identifier.urihttps://hdl.handle.net/2144/40629
dc.description.abstractDeficits in face processing and social impairment are core characteristics of autism spectrum disorder. The present work examined 7-month-old infants at high-risk for developing autism and typically developing controls at low-risk, using a face perception task designed to differentiate between the effects of face identity and facial emotions on neural response using functional Near-Infrared Spectroscopy. In addition, we employed independent component analysis, as well as a novel method of condition-related component selection and classification to identify group differences in hemodynamic waveforms and response distributions associated with face and emotion processing. The results indicate similarities of waveforms, but differences in the magnitude, spatial distribution, and timing of responses between groups. These early differences in local cortical regions and the hemodynamic response may, in turn, contribute to differences in patterns of functional connectivity.en_US
dc.description.sponsorshipThis work was made possible, in part, by grants from Autism Speaks, the Simons Foundation, and the NIDCD (R21 DC 08637 and R01 DC 10290) to Helen Tager-Flusberg and Charles A. Nelson, the NIMH-funded Stuart T. Hauser Research Training Program in Biological and Social Psychiatry and a NARSAD Abrams Young Investigator Award (to Jennifer B. Wagner) and the Hugh Hampton Young Memorial Foundation, the NIH-funded Advanced Multimodal Neuroimaging Training Program, and the NIH-funded Neuroimaging Training Program (to Sharon E. Fox). Direct correspondence to the last author at Charles.nelson@childrens.harvard.edu. (Autism Speaks; Simons Foundation; R21 DC 08637 - NIDCD; R01 DC 10290 - NIDCD; Helen Tager-Flusberg; NIMH; NARSAD; Hugh Hampton Young Memorial Foundation; NIH)en_US
dc.format.extent18 pagesen_US
dc.languageEnglish
dc.language.isoen_US
dc.publisherFRONTIERS RESEARCH FOUNDATIONen_US
dc.relation.ispartofFRONTIERS IN HUMAN NEUROSCIENCE
dc.rights"Copyright: © 2013 Fox, Wagner, Shrock, Tager-Flusberg and Nelson. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc."en_US
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/
dc.subjectScience & technologyen_US
dc.subjectSocial sciencesen_US
dc.subjectLife sciences & biomedicineen_US
dc.subjectNeurosciencesen_US
dc.subjectPsychologyen_US
dc.subjectNeurosciences & neurologyen_US
dc.subjectAutismen_US
dc.subjectfNIRSen_US
dc.subjectFace processingen_US
dc.subjectNear-infrared spectroscopyen_US
dc.subjectCognitive developmenten_US
dc.subjectIndependent component analysisen_US
dc.subjectNear-infrared spectroscopyen_US
dc.subject6-month-old infantsen_US
dc.subjectFace perceptionen_US
dc.subjectHuman brainen_US
dc.subjectRecognitionen_US
dc.subjectActivationen_US
dc.subjectCortexen_US
dc.subjectGazeen_US
dc.subjectCircuitryen_US
dc.subjectExperimental psychologyen_US
dc.subjectCognitive sciencesen_US
dc.titleNeural processing of facial identity and emotion in infants at high-risk for autism spectrum disordersen_US
dc.typeArticleen_US
dc.identifier.doi10.3389/fnhum.2013.00089
pubs.elements-sourceweb-of-scienceen_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Arts & Sciencesen_US
pubs.organisational-groupBoston University, College of Arts & Sciences, Department of Psychological & Brain Sciencesen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0002-8768-5414 (Tager-Flusberg, Helen)
dc.identifier.mycv34324


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"Copyright:  © 2013 Fox, Wagner, Shrock, Tager-Flusberg and Nelson. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc."
Except where otherwise noted, this item's license is described as "Copyright: © 2013 Fox, Wagner, Shrock, Tager-Flusberg and Nelson. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc."