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dc.contributor.authorPassingham, R. E.en_US
dc.contributor.authorChung, A.en_US
dc.contributor.authorGoparaju, B.en_US
dc.contributor.authorCowey, A.en_US
dc.contributor.authorVaina, Lucia M.en_US
dc.date.accessioned2020-05-12T12:35:52Z
dc.date.available2020-05-12T12:35:52Z
dc.date.issued2014-09-25
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343357100007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=6e74115fe3da270499c3d65c9b17d654
dc.identifier.citationR.E. Passingham, A. Chung, B. Goparaju, A. Cowey, L.M. Vaina. 2014. "Using action understanding to understand the left inferior parietal cortex in the human brain." BRAIN RESEARCH, Volume 1582, pp. 64 - 76 (13). https://doi.org/10.1016/j.brainres.2014.07.035
dc.identifier.issn0006-8993
dc.identifier.issn1872-6240
dc.identifier.urihttps://hdl.handle.net/2144/40780
dc.descriptionPublished in final edited form as: Brain Res. 2014 September 25; 1582: 64–76. doi:10.1016/j.brainres.2014.07.035.en_US
dc.description.abstractHumans have a sophisticated knowledge of the actions that can be performed with objects. In an fMRI study we tried to establish whether this depends on areas that are homologous with the inferior parietal cortex (area PFG) in macaque monkeys. Cells have been described in area PFG that discharge differentially depending upon whether the observer sees an object being brought to the mouth or put in a container. In our study the observers saw videos in which the use of different objects was demonstrated in pantomime; and after viewing the videos, the subject had to pick the object that was appropriate to the pantomime. We found a cluster of activated voxels in parietal areas PFop and PFt and this cluster was greater in the left hemisphere than in the right. We suggest a mechanism that could account for this asymmetry, relate our results to handedness and suggest that they shed light on the human syndrome of apraxia. Finally, we suggest that during the evolution of the hominids, this same pantomime mechanism could have been used to ‘name’ or request objects.en_US
dc.description.sponsorshipWe thank Steve Wise for very detailed comments on a draft of this paper. We thank Rogier Mars for help with identifying the areas that were activated in parietal cortex and for comments on a draft of this paper. Finally, we thank Michael Nahhas for help with the imaging figures. This work was supported in part by the NIH grant RO1NS064100 to LMV. (RO1NS064100 - NIH)en_US
dc.format.extentp. 64 - 76en_US
dc.languageEnglish
dc.language.isoen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofBRAIN RESEARCH
dc.subjectScience & technologyen_US
dc.subjectLife sciences & biomedicineen_US
dc.subjectNeurosciencesen_US
dc.subjectNeurosciences & neurologyen_US
dc.subjectInferior parietal cortexen_US
dc.subjectHuman brainen_US
dc.subjectAction understandingen_US
dc.subjectAction observationen_US
dc.subjectPantomimeen_US
dc.subjectApraxiaen_US
dc.subjectCerebral dominanceen_US
dc.subjectTractography-based parcellationen_US
dc.subjectSurface-based analysisen_US
dc.subjectPrefrontal cortexen_US
dc.subjectMacaque monkeyen_US
dc.subjectPremotor cortexen_US
dc.subjectTool useen_US
dc.subjectVentral premotoren_US
dc.subjectFrontal cortexen_US
dc.subjectNeuronsen_US
dc.subjectFMRIen_US
dc.subjectAdulten_US
dc.subjectBrain mappingen_US
dc.subjectFemaleen_US
dc.subjectFrontal lobeen_US
dc.subjectFunctional lateralityen_US
dc.subjectHanden_US
dc.subjectHumansen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectMaleen_US
dc.subjectMotion perceptionen_US
dc.subjectNeuropsychological testsen_US
dc.subjectParietal lobeen_US
dc.subjectPhotic stimulationen_US
dc.subjectVideo recordingen_US
dc.subjectYoung adulten_US
dc.subjectCognitive sciencesen_US
dc.subjectPsychologyen_US
dc.subjectNeurology & neurosurgeryen_US
dc.titleUsing action understanding to understand the left inferior parietal cortex in the human brainen_US
dc.typeArticleen_US
dc.description.versionAccepted manuscripten_US
dc.identifier.doi10.1016/j.brainres.2014.07.035
pubs.elements-sourceweb-of-scienceen_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Engineeringen_US
pubs.organisational-groupBoston University, College of Engineering, Department of Biomedical Engineeringen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0002-5636-8352 (Vaina, LM)
dc.identifier.mycv36872


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