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dc.contributor.advisorGarcia-Diaz, J. Fernandoen_US
dc.contributor.advisorMoussavi, Minaen_US
dc.contributor.authorBelding, Emilyen_US
dc.date.accessioned2020-06-12T18:07:11Z
dc.date.available2020-06-12T18:07:11Z
dc.date.issued2020
dc.identifier.urihttps://hdl.handle.net/2144/41185
dc.description.abstractThe prevalence of pregnancies complicated by chronic kidney disease (CKD) is increasing. Yet, CKD in pregnancy tends to be under-diagnosed, as women of childbearing age are not regularly screened for renal dysfunction, nor is screening incorporated into routine pregnancy follow up. Further, renal dysfunction has significant implications for maternal and fetal outcomes, with degree of renal dysfunction at conception being the most important prognostic factor. It is established that the risk for poorer renal, maternal and fetal outcomes, increases incrementally with severity of CKD, with intrauterine death and progression to end-stage renal disease (ESDR) associated with severe CKD. However, it is difficult to predict which CKD pregnancies will lead to poor outcomes as the definition of CKD in pregnancy is not uniform between studies, nor are measurement parameters. This paucity of data prevents the establishment of a standard of care protocol and leaves clinicians ill-equipped to care for and manage this complex patient cohort. This review discusses renal, maternal and fetal outcomes in CKD pregnancies as presented by the literature, in order to demonstrate the contradictions in data and gaps in knowledge surrounding this topic, as well as the need for a general management algorithm.en_US
dc.language.isoen_US
dc.subjectPhysiologyen_US
dc.subjectChronic kidney disease (CKD)en_US
dc.subjectCKD in Pregnancyen_US
dc.subjectCKD managementen_US
dc.subjectMaternal outcomesen_US
dc.titleA review of the implications of chronic kidney disease in pregnancy on maternal and fetal outcomesen_US
dc.typeThesis/Dissertationen_US
dc.date.updated2020-06-12T16:21:42Z
etd.degree.nameMaster of Scienceen_US
etd.degree.levelmastersen_US
etd.degree.disciplineMedical Sciencesen_US
etd.degree.grantorBoston Universityen_US
dc.identifier.orcid0000-0003-4872-4668


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