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dc.contributor.advisorOhira, Taisukeen_US
dc.contributor.authorAhmad, Bushra A M Aen_US
dc.date.accessioned2020-07-30T15:16:44Z
dc.date.available2020-07-30T15:16:44Z
dc.date.issued2020
dc.identifier.urihttps://hdl.handle.net/2144/41343
dc.description.abstractBACKGROUND: Recently osseodensification has been introduced as a novel approach to management of the recipient site. The concept had been described in 2013 by Huwais which has revolutionized the way we approach an osteotomy site as we may obtain densification of the bone rather than its complete removal. AIM: We hypothesize that proper manipulation of the recipient site will induce cellular activities to accelerate new bone formation. We compared bone formation in a critical defect created by the osseodensification method or regular osteotomy under ex-vivo static calvarial culture. MATERIALS AND METHODS: Under sterile conditions, calvaria from 7-9-day-old neonatal CD-1 mice (n = 15) were dissected and trimmed. Densah™ burs were used to create 2.0 mm diameter defects. Clockwise rotation of the bur produced "Conventional Osteotomy," whereas counter-clockwise rotation created "Osseodensification." Five randomly selected calvaria halves for control and test groups were used to evaluate morphological changes, at 7, 14, and 28 days utilizing the Image J software. Statistical analyses were performed using SPSS software. RESULTS: Defect closure was significantly greater in the osseodensification group compared to the conventional group at post-operative day7 (p = 0.028), day 14 (p = 0.046) and day 28 (p=0.015). The original defects in both groups were not significantly different. CONCLUSION: Results showed that osseodensification lead to faster wound healing. Clinical studies have shown that osseodensification leads to better bone density around implants. These outcomes suggest that the compressed edge of a bone defect can accelerate the healing cascade by increasing cellular activity.en_US
dc.language.isoen_US
dc.subjectDentistryen_US
dc.subjectImplanten_US
dc.subjectOsseodensificationen_US
dc.subjectStabilityen_US
dc.titleOsseodensification-induced bone healing in mouse calvaria under static conditionen_US
dc.typeThesis/Dissertationen_US
dc.date.updated2020-07-29T16:02:25Z
etd.degree.nameMaster of Science in Designen_US
etd.degree.levelmastersen_US
etd.degree.disciplinePeriodontologyen_US
etd.degree.grantorBoston Universityen_US


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