Theses & Dissertations
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Harnessing the power of light in nanopore sensing and biomedical 3D printing applications
(2021)Light is a ubiquitous form of energy used in many disciplines and industry sectors. Biomedical applications that harness the distinctive properties of light are rapidly growing in many areas, such as medical imaging, ... -
Integrated electrochemical device to screen for liver function at the point-of-care
(2021)Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) continue to be a significant global burden, disproportionately affecting low- and middle-income countries (LMICs). While much progress has been made in treating these ... -
Techniques for single-shot volumetric fluorescence imaging
(2021)Rapid development of genetically encoded fluorescent indicators has provided a diverse chemical toolkit to probe complex biological systems, leading to the expansion of fluorescence microscopy for biological research and ... -
FPGA-based high-performance neural network acceleration
(2021)In the last ten years, Artificial Intelligence through Deep Neural Networks (DNNs) has penetrated virtually every aspect of science, technology, and business. Advances are rapid with thousands of papers being published ... -
Sex-biased and xenobiotic-responsive long non-coding RNAs in mouse liver: sub-cellular localization, liver cell-type specificity, and knockdown by epigenetic reprogramming
(2021)Long non-coding RNAs (lncRNAs) are key regulators of gene expression, playing crucial roles in biological processes across many species, tissues and diseases. The liver is a highly responsive organ in which large changes ... -
Intelligent middleware for HPC systems to improve performance and energy cost efficiency
(2021)High-performance computing (HPC) systems play an essential role in large-scale scientific computations. As the number of nodes in HPC systems continues to increase, their power consumption leads to larger energy costs. The ... -
Advanced gene expression control in therapeutic human cells using synthetic transcriptional programs
(2021)An enduring goal of synthetic biology is to engineer cells to perform increasingly sophisticated therapeutic functions. Inspired by natural gene expression programs that elegantly govern diverse cellular behaviors, numerous ... -
Control and optimization methods for problems in intelligent transportation systems
(2021)This thesis aims to address three research topics in intelligent transportation systems which include multi-intersection traffic light control based on stochastic flow models with delays and blocking, optimization of ... -
Digital volume correlation as a method for estimating load-induced deformations in the human spine
(2021)Digital volume correlation (DVC) is a computational tool used to measure a 3D displacement field between a pair of 3D images (from, for example, magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, etc.). ... -
Real-time coherent X-ray studies of kinetics and dynamics in self-organized ion beam nanopatterning
(2021)Real-time coherent Grazing-Incidence Small-Angle X-ray Scattering was used to investigate the average kinetics and the fluctuation dynamics during self-organized ion beam nano-patterning of two semiconductor surfaces: ...