Theses & Dissertations
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URI: http://hdl.handle.net/2144/898
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Multiplexed antibody kinetics using the Interferometric Reflectance Imaging Sensor
(2019)Label free detection of biologically relevant binding pairs has provided critical insight into the characterization of reagents used in both therapeutic and diagnostic applications. The Interferometric Reflectance Imaging ... -
Current state of precision therapy for the management of lung adenocarcinoma
(2019)Lung adenocarcinoma (LUAD) is a subtype of non small-cell lung cancer that has been characterized by late stage diagnosis and poor clinical outcomes. Recent advances in tumor genotyping and precision therapies have shifted ... -
Peripheral blood biomarkers in youth with bipolar disorder: a systematic review
(2019)Bipolar disorder (BD) is a chronic, progressive illness characterized by fluctuations in mood. It is associated with psychosocial and cognitive impairment that can affect a person’s life at home, at work or school, and in ... -
Glass population study and discrimination of glass samples using Glass Refractive Index Measurement III and scanning electron microscopy/energy dispersive X-ray spectroscopy
(2019)Glass is a hard, amorphous, and transparent or translucent substance, and it is examined in forensic science to place a person or object at a scene or with a victim when a crime is committed. Due to its brittle nature ... -
Detection of saliva using Seratec Amylase Paper
(2019)Biological fluids, like saliva, are commonly encountered in forensic casework. The ability to locate and identify the type of biological fluid on a piece of evidence can lead to further testing including DNA extraction and ... -
Developing a predictive mortality risk algorithm for preterm neonates requiring surgical intervention at Boston Children's Hospital
(2019)INTRODUCTION: Preterm infants have high mortality rates worldwide (Blencowe et al., 2013). The leading causes of infant mortality in the United States are preterm birth, low birth weight, and birth defects (Ely, Driscoll, ... -
A casework review of sexual assault evidence collection kit smear slides received by Boston Police Department crime laboratory and reported time since intercourse
(2019)In the field of forensic biology, the term “time since intercourse (TSI)” is used to describe the approximate time elapsed between an alleged sexual assault and the collection of a Sexual Assault Evidence Collection Kit ... -
Analysis of microcystins LR, YR, and RR in biological fluids by 2D-LC technology
(2019)Algae “super blooms” are a commonly encountered environmental issue in fresh and brackish water that occurs due to the buildup of cyanobacteria. Many of the commonly encountered cyanobacteria such as Mycrocystis aeruginosa ... -
To evaluate the safety and efficacy of intra-articular tranexamic acid in primary total joint arthoplasty
(2019)BACKGROUND: Tranexamic acid (TXA) has become highly utilized in total joint arthroplasties for its anti-fibrinolytic effect. Recently, intra-articular application of TXA has become popular for its avoidance of systemic ... -
Mechanisms that regulate pro-inflammatory cytokine expression in CD4+ T cells
(2019)Cytokines released by innate immune cells initiate pathways that drive the differentiation of CD4+ T cells into subsets with defined patterns of cytokine secretion. Type I interferons (IFNs) are cytokines that decrease a ...
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