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  Understanding the role of ALC1-dependent chromatin remodeling in mediating PARP-inhibitor sensitivity 

  Deraska, Peter (2020)

  OBJECTIVE: Despite advancement in targeted therapeutics, women’s cancers remain particularly deadly. The response to Poly (ADP-ribose) Polymerase (PARP) inhibitors, a prominent targeted therapy indicated for use in these ...
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  Direct cardiac actions of Ertugliflozin 

  Croteau, Dominique Christina (2020)

  Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors block renal glucose reabsorption and have shown marked cardiac protection in type 2 diabetics, and surprisingly, also in non-diabetics. However, the mechanism by which ...
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  The role of transmembrane immunoglobulin domain containing-1 in colon cancer 

  de la Cena, Kyle Oliver (2020)

  Colorectal Cancer (CRC) is one of the most common cancers worldwide. Although various genetic and environmental mechanisms have been identified, the full molecular mechanisms deriving CRC tumorigenesis remain largely ...
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  Electromyography muscle testing demonstrates a hands-free single crutch maintains superior in-phase muscular contractions than standard axillary crutches 

  Dewar, Cuyler (2020)

  BACKGROUND: In order to maintain non-weight bearing restrictions of the lower extremity, an assistive device must be utilized. Currently most devices require the restricted limb to be held in a static position while the ...
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  Pain and college adjustment study 

  Dhaliwal, Harshaan (2020)

  BACKGROUND: Health issues facing university students have been an area of increasing concern, with the frequency of anxiety and depression-related disorders rising significantly over the past few years. One characteristic ...
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  Cellulitis and breast cancer-related lymphedema: risk factors and timing 

  Havens, Lauren Michael (2020)

  PURPOSE: This study investigated the risk factors for cellulitis infection, the median time to onset of low volume swelling (5 to 10% relative volume change (RVC) and breast cancer-related lymphedema (BCRL) (≥10% RVC) after ...
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  Whole genome doubling confers unique genetic vulnerabilities on tumor cells 

  DiDomizio, Amanda (2020)

  Whole genome doubling (WGD) generates genetically unstable tetraploid cells that fuel tumorigenesis. Cells that undergo WGD must acquire adaptive characteristics to accommodate their tetraploid state, and these adaptations ...
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  The signal feature difference between two intracranial MR angiography sequences as an imaging biomarker for neurological health 

  Gould, Anders (2020)

  SNAP and TOF are two non-contrast enhanced intracranial magnetic resonance angiography (MRA) techniques. Both techniques rely on incoming blood to produce a signal, although they have different sensitivity to blood flow ...
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  Development of a risk index for postoperative mortality or ICU admission in preterm and early term neonates undergoing surgery 

  Feichtmeier, Joseph (2020)

  OBJECTIVE: Despite recent scientific and technological advancements preterm birth remains one of the leading causes of neonatal mortality worldwide. With annual increases in the prevalence of preterm birth over the last ...
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  Characterizing induced gene expression in Shigella flexneri following bile salt exposure 

  Carey, James (2020)

  The Shigella species cause millions of cases of watery or bloody diarrhea each year in developing countries, with children under the age of five years most vulnerable to infection. Emerging strains of multidrug resistant ...

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