Goldman School of Dental Medicine
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URI: http://hdl.handle.net/2144/967
The goal of the Goldman School of Dental Medicine is to provide dental professionals with ongoing training throughout their dental careers. Through education and research our students shape the future of dental medicine. We offer a host of predoctoral and postdoctoral degrees and certificate programs from the Doctor of Dental Medicine (DMD) to 11 postgraduate degrees. Students choose from a wide range of specialties including general and pediatric dentistry, endodontics, orthodontics, prosthodontics, oral and maxillofacial surgery and pathology, and implantology. Students may also combine research programs with clinical training to earn a Certificate of Advanced Graduate Study (CAGS) along with their MS in Dentistry.
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Toll-Like Receptor-2 Mediates Diet and/or Pathogen Associated Atherosclerosis: Proteomic Findings
(Public Library of Science, 2008-9-12)BACKGROUND. Accumulating evidence implicates a fundamental link between the immune system and atherosclerosis. Toll-like receptors are principal sensors of the innate immune system. Here we report an assessment of the role ... -
The Jacob2 Lectin of the Entamoeba Histolytica Cyst Wall Binds Chitin and Is Polymorphic
(Public Library of Science, 2010-7-20)BACKGROUND. The infectious and diagnostic form of Entamoeba histolytica (Eh), cause of amebic dysentery and liver abscess, is the quadranucleate cyst. The cyst wall of Entamoeba invadens (Ei), a model for Eh, is composed ... -
Risk of Tooth Loss After Cigarette Smoking Cessation
(Centers for Disease Control and Prevention, 2006-9-15)INTRODUCTION. Little is known about the effect of cigarette smoking cessation on risk of tooth loss. We examined how risk of tooth loss changed with longer periods of smoking abstinence in a prospective study of oral health ... -
Giardia Cyst Wall Protein 1 Is a Lectin That Binds to Curled Fibrils of the GalNAc Homopolymer
(Public Library of Science, 2010-8-19)The infectious and diagnostic stage of Giardia lamblia (also known as G. intestinalis or G. duodenalis) is the cyst. The Giardia cyst wall contains fibrils of a unique β-1,3-linked N-acetylgalactosamine (GalNAc) homopolymer ... -
A New Brief Measure of Oral Quality of Life
(Centers for Disease Control and Prevention, 2008-3-15)INTRODUCTION. We developed a brief measure of the impact of oral conditions on individual functioning and well-being, known as oral quality of life. METHODS. Among older male veterans (N = 827) and community dental patients ... -
Discovery of a Novel and Rich Source of Gluten-Degrading Microbial Enzymes in the Oral Cavity
(Public Library of Science, 2010-10-11)BACKGROUND. Celiac disease is a T cell mediated-inflammatory enteropathy caused by the ingestion of gluten in genetically predisposed individuals carrying HLA-DQ2 or HLA-DQ8. The immunogenic gliadin epitopes, containing ... -
Trichomonas Transmembrane Cyclases Result from Massive Gene Duplication and Concomitant Development of Pseudogenes
(Public Library of Science, 2010-8-3)BACKGROUND. Trichomonas vaginalis has an unusually large genome (∼160 Mb) encoding ∼60,000 proteins. With the goal of beginning to understand why some Trichomonas genes are present in so many copies, we characterized here ... -
Bioinformatics Analysis of Macrophages Exposed to Porphyromonas gingivalis: Implications in Acute vs. Chronic Infections
(Public Library of Science, 2010-12-23)BACKGROUND. Periodontitis is the most common human infection affecting tooth-supporting structures. It was shown to play a role in aggravating atherosclerosis. To deepen our understanding of the pathogenesis of this disease, ... -
Evidence for a "Wattle and Daub" Model of the Cyst Wall of Entamoeba
(Public Library of Science, 2009-7-3)The cyst wall of Entamoeba invadens (Ei), a model for the human pathogen Entamoeba histolytica, is composed of fibrils of chitin and three chitin-binding lectins called Jacob, Jessie3, and chitinase. Here we show chitin, ... -
Activin A Expression Regulates Multipotency of Mesenchymal Progenitor Cells
(BioMed Central, 2010-5-4)INTRODUCTION. Bone marrow (BM) stroma currently represents the most common and investigated source of mesenchymal progenitor cells (MPCs); however, comparable adult progenitor or stem cells have also been isolated from a ... -
Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice
(Nature Publishing Group, 2009-12-01)We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical ... -
Identification of Positive Regulators of the Yeast Fps1 Glycerol Channel
(Public Library of Science, 2009-11-26)The yeast Fps1 protein is an aquaglyceroporin that functions as the major facilitator of glycerol transport in response to changes in extracellular osmolarity. Although the High Osmolarity Glycerol pathway is thought to ... -
Cumulative Lead Exposure and Tooth Loss in Men: The Normative Aging Study
(National Institute of Environmental Health Sciences, 2009-10)BACKGROUND. Individuals previously exposed to lead remain at risk because of endogenous release of lead stored in their skeletal compartments. However, it is not known if long-term cumulative lead exposure is a risk factor ... -
Immune Response of Macrophages from Young and Aged Mice to the Oral Pathogenic Bacterium Porphyromonas Gingivalis
(BioMed Central, 2010-11-29)Periodontal disease is a chronic inflammatory gum disease that in severe cases leads to tooth loss. Porphyromonas gingivalis (Pg) is a bacterium closely associated with generalized forms of periodontal disease. Clinical ... -
The Methodological Quality of Systematic Reviews Comparing Temporomandibular Joint Disorder Surgical and Non-Surgical Treatment
(BioMed Central, 2008-9-26)BACKGROUND: Temporomandibular joint disorders (TMJD) are multifactor, complex clinical problems affecting approximately 60–70% of the general population, with considerable controversy about the most effective treatment. ... -
FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats
(American Diabetes Association, 2009-1-23)OBJECTIVE: To investigate early events leading to microvascular cell loss in diabetic retinopathy. RESEARCH DESIGN AND METHODS: FOXO1 was tested in vivo by DNA binding activity and by nuclear translocation in microvascular ...
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