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Biomedical engineering is advancing rapidly and producing important innovations that improve our quality of life. From understanding the human genome to pioneering surgical tools, Boston University biomedical engineers are committed the advancement of research and education in biotechnology, biomolecular engineering, sensory systems, cardiopulmonary engineering, neuroscience, micro-and nano-systems and biomechanics and biomaterials.


Biomedical Engineering
John A. White, Ph.D., Chairman
44 Cummington St., Room 403
Phone: (617) 353-2805
Fax: (617) 353-6766

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  • Reconstruction of 1,000 projection neurons reveals new cell types and organization of long-range connectivity in the mouse brain 

    Winnubst, Johan; Bas, Erhan; Ferreira, Tiago A.; Wu, Zhuhao; Economo, Michael N.; Edson, Patrick; Arthur, Ben J.; Bruns, Christopher; Rokicki, Konrad; Schauder, David; Olbris, Donald J.; Murphy, Sean D.; Ackerman, David G.; Arshadi, Cameron; Baldwin, Perry; Blake, Regina; Elsayed, Ahmad; Hasan, Mashtura; Ramirez, Daniel; Dos Santos, Bruno; Weldon, Monet; Zafar, Amina; Dudman, Joshua T.; Gerfen, Charles R.; Hantman, Adam W.; Korff, Wyatt; Sternson, Scott M.; Spruston, Nelson; Svoboda, Karel; Chandrashekar, Jayaram (2019-09-19)
    Neuronal cell types are the nodes of neural circuits that determine the flow of information within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides an essential descriptor of cell type and ...
  • Automatic graph-based modeling of brain microvessels captured with two-photon microscopy 

    Damseh, Rafat; Pouliot, Philippe; Gagnon, Louis; Sakadzic, Sava; Boas, David; Cheriet, Farida; Lesage, Frederic (2019-11)
    Graph models of cerebral vasculature derived from two-photon microscopy have shown to be relevant to study brain microphysiology. Automatic graphing of these microvessels remain problematic due to the vascular network ...
  • A computational paradigm for real-time MEG neurofeedback for dynamic allocation of spatial attention 

    Rana, Kunjan D.; Khan, Sheraz; Hämäläinen, Matti S.; Vaina, Lucia (BioMed Central, 2020-06-12)
    BACKGROUND: Neurofeedback aids volitional control of one's own brain activity using non-invasive recordings of brain activity. The applications of neurofeedback include improvement of cognitive performance and treatment ...
  • Active learning for efficient microfluidic design automation 

    McIntyre, David; Lashkaripour, Ali; Densmore, Douglas (IWBDA, 2020-08-03)
    Droplet microfluidics has the potential to eliminate the testing bottleneck in synthetic biology by screening biological samples encapsulated in water-in-oil emulsions at unprecedented throughput. Sophisticated screens ...
  • Efficient large-scale microfluidic design-space exploration: from data to model to data 

    Lashkaripour, Ali; McIntyre, David; Densmore, Douglas (IWBDA, 2020-08-03)
    Droplet microfluidics is well poised to improve the gold standard in many fields such as synthetic biology. However, the lack of available design automation tools that can create a microfluidic droplet generator based on ...
  • Dependence of the MR signal on the magnetic susceptibility of blood studied with models based on real microvascular networks 

    Cheng, Xiaojun; Berman, Avery J. L.; Polimeni, Jonathan R.; Buxton, Richard B.; Gagnon, Louis; Devor, Anna; Sakadzic, Sava; Boas, David A. (Wiley, 2019-06)
    PURPOSE: The primary goal of this study was to estimate the value of beta , the exponent in the power law relating changes of the transverse relaxation rate and intra-extravascular local magnetic susceptibility differences ...
  • Awake mouse imaging: from two-photon microscopy to blood oxygen level-dependent functional magnetic resonance imaging 

    Desjardins, Michèle; Kilic, Kivilcim; Thunemann, Martin; Mateo, Celine; Holland, Dominic; Ferri, Christopher G. L.; Cremonesi, Jonathan A.; Li, Baoqiang; Cheng, Qun; Weldy, Kimberly L.; Saisan, Payam A.; Kleinfeld, David; Komiyama, Takaki; Liu, Thomas T.; Bussell, Robert; Wong, Eric C.; Scadeng, Miriam; Dunn, Andrew K.; Boas, David A.; Sakadzic, Sava; Mandeville, Joseph B.; Buxton, Richard B.; Dale, Anders M.; Devor, Anna (Elsevier, 2019-06)
    BACKGROUND: Functional magnetic resonance imaging (fMRI) in awake behaving mice is well positioned to bridge the detailed cellular-level view of brain activity, which has become available owing to recent advances in ...
  • Effect of residual interatrial shunt on migraine burden after transcatheter closure of patent foramen ovale 

    Ben-Assa, Eyal; Rengifo-Moreno, Pablo; Al-Bawardy, Rasha; Kolte, Dhaval; Cigarroa, Ricardo; Cruz-Gonzalez, Ignacio; Sakhuja, Rahul; Elmariah, Sammy; Pomerantsev, Eugene; Vaina, Lucia M.; Ning, MingMing; Buonanno, Ferdinando S.; Hung, Judy W.; Inglessis, Ignacio; Palacios, Igor F. (JACC, 2020-02-10)
    OBJECTIVES: This study sought to evaluate the long-term effect of transcatheter patent foramen ovale (PFO) closure on migraineurs with and without aura and examine the effect of residual right-to-left shunt. BACKGROUND: ...
  • Epistatic interaction maps relative to multiple metabolic phenotypes 

    Snitkin, Evan S.; Segrè, Daniel (Public Library of Science, 2011-02-01)
    An epistatic interaction between two genes occurs when the phenotypic impact of one gene depends on another gene, often exposing a functional association between them. Due to experimental scalability and to evolutionary ...
  • Acoustic facilitation of object movement detection during self-motion 

    Calabro, Finnegan J.; Soto-Faraco, S.; Vaina, Lucia M. (The Royal Society, 2011-09-22)
    In humans, as well as most animal species, perception of object motion is critical to successful interaction with the surrounding environment. Yet, as the observer also moves, the retinal projections of the various motion ...

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