Biomedical Engineering
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URI: http://hdl.handle.net/2144/974
Biomedical engineering is advancing rapidly and producing important innovations that improve our quality of life. From understanding the human genome to pioneering surgical tools, Boston University biomedical engineers are committed the advancement of research and education in biotechnology, biomolecular engineering, sensory systems, cardiopulmonary engineering, neuroscience, micro-and nano-systems and biomechanics and biomaterials.
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Biomedical Engineering
John A. White, Ph.D., Chairman
44 Cummington St., Room 403
Phone: (617) 353-2805
Fax: (617) 353-6766
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Cortical gamma rhythms modulate NMDAR-mediated spike timing dependent plasticity in a biophysical model
(Public Library of Science, 2009-12-01)Spike timing dependent plasticity (STDP) has been observed experimentally in vitro and is a widely studied neural algorithm for synaptic modification. While the functional role of STDP has been investigated extensively, ... -
Representation of time-varying stimuli by a network exhibiting oscillations on a faster time scale
(Public Library of Science, 2009-05-01)Sensory processing is associated with gamma frequency oscillations (30–80 Hz) in sensory cortices. This raises the question whether gamma oscillations can be directly involved in the representation of time-varying stimuli, ... -
Automating functional enzyme screening & characterization
(International Workshop on Bio-Design Automation (IWBDA), 2018-08-03)Microfluidics continue to gain traction as an inexpensive alternative to standard multi-well plate-based, and flow cytometry- based, assay platforms. These devices are especially useful for the types of ultra-high throughput ... -
Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix
(2015-08-14)Despite the crucial role of extracellular matrix (ECM) in directing cell fate in healthy and diseased tissues--particularly in development, wound healing, tissue regeneration and cancer--the mechanisms that direct the ... -
Using molecular mechanics to predict bulk material properties of fibronectin fibers
(2012)The structural proteins of the extracellular matrix (ECM) form fibers with finely tuned mechanical properties matched to the time scales of cell traction forces. Several proteins such as fibronectin (Fn) and fibrin undergo ... -
Pushing indium phosphide quantum dot emission deeper into the near infrared
(Society of Photo-optical Instrumentation Engineers, 2018-02-01)Cadmium-free near infrared (NIR) emitting quantum dots (QDs) have significant potential for multiplexed tissue-depth imaging applications in the first optical tissue window (i.e., 650 – 900 nm). Indium phosphide (InP) ... -
Optogenetic activation of accessory olfactory bulb input to the forebrain differentially modulates investigation of opposite versus same-sex urinary chemosignals and stimulates mating in male mice
(2017-03)Surgical or genetic disruption of vomeronasal organ (VNO)-accessory olfactory bulb (AOB) function previously eliminated the ability of male mice to processes pheromones that elicit territorial behavior and aggression. By ... -
Silk-fibronectin protein alloy fibres support cell adhesion and viability as a high strength, matrix fibre analogue
(2017-04-05)Silk is a natural polymer with broad utility in biomedical applications because it exhibits general biocompatibility and high tensile material properties. While mechanical integrity is important for most biomaterial ... -
Förster resonance energy transfer between quantum dot donors and quantum dot acceptors
(2015-06-05)Förster (or fluorescence) resonance energy transfer amongst semiconductor quantum dots (QDs) is reviewed, with particular interest in biosensing applications. The unique optical properties of QDs provide certain advantages ... -
Quantifying engineered nanomaterial toxicity: comparison of common cytotoxicity and gene expression measurements
(2017-11-09)BACKGROUND: When evaluating the toxicity of engineered nanomaterials (ENMS) it is important to use multiple bioassays based on different mechanisms of action. In this regard we evaluated the use of gene expression and ...
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