Biomedical Engineering
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URI: http://hdl.handle.net/2144/974
Biomedical engineering is advancing rapidly and producing important innovations that improve our quality of life. From understanding the human genome to pioneering surgical tools, Boston University biomedical engineers are committed the advancement of research and education in biotechnology, biomolecular engineering, sensory systems, cardiopulmonary engineering, neuroscience, micro-and nano-systems and biomechanics and biomaterials.
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Biomedical Engineering
John A. White, Ph.D., Chairman
44 Cummington St., Room 403
Phone: (617) 353-2805
Fax: (617) 353-6766
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Collagen XII mediated cellular and extracellular mechanisms regulate establishment of tendon structure and function
(Elsevier BV, 2021-01)Tendons have a uniaxially aligned structure with a hierarchical organization of collagen fibrils crucial for tendon function. Collagen XII is expressed in tendons and has been implicated in the regulation of fibrillogenesis. ... -
Tendon exhibits complex poroelastic behavior at the nanoscale as revealed by high-frequency AFM-based rheology
Tendons transmit load from muscle to bone by utilizing their unique static and viscoelastic tensile properties. These properties are highly dependent on the composition and structure of the tissue matrix, including the ... -
Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease
(2020-09)BACKGROUND: Identifying and understanding the functional role of genetic risk factors for Alzheimer disease (AD) has been complicated by the variability of genetic influences across brain regions and confounding with ... -
Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters
(2020-10)SIGNIFICANCE: The optical properties of biological samples provide information about the structural characteristics of the tissue and any changes arising from pathological conditions. Optical coherence tomography (OCT) has ... -
Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity
(2020-04-30)White adipose tissue plays an important role in physiological homeostasis and metabolic disease. Different fat depots have distinct metabolic and inflammatory profiles and are differentially associated with disease risk. ... -
Correlative intravital imaging of cGMP signals and vasodilation in mice
(2014)Cyclic guanosine monophosphate (cGMP) is an important signaling molecule and drug target in the cardiovascular system. It is well known that stimulation of the vascular nitric oxide (NO)-cGMP pathway results in vasodilation. ... -
Correlation structure in micro-ECoG recordings is described by spatially coherent components
(2019)Electrocorticography (ECoG) is becoming more prevalent due to improvements in fabrication and recording technology as well as its ease of implantation compared to intracortical electrophysiology, larger cortical coverage, ... -
A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis
(2018-10-16)Mechanisms that limit thrombosis are poorly defined. One of the few known endogenous platelet inhibitors is nitric oxide (NO). NO activates NO sensitive guanylyl cyclase (NO-GC) in platelets, resulting in an increase of ... -
Publisher correction: a shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis
(2018-11-20)The original version of this Article contained an error in the description of Supplementary Movie 4, in which the final sentence was inadvertently truncated. The HTML has been updated to include a corrected version of the ...
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