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URI: http://hdl.handle.net/2144/987

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  • Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits 

    Kondabolu, Krishnakanth; Roberts, Erik A.; Bucklin, Mark; McCarthy, Michelle M.; Kopell, Nancy; Han, Xue (2016-05-31)
    Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease ...
  • How proteins bind macrocycles 

    Villar, Elizabeth A.; Beglov, Dmitri; Chennamadhavuni, Spandan; Porco, John A.; Kozakov, Dima; Vajda, Sandor; Whitty, Adrian (2014-09)
    The potential utility of synthetic macrocycles (MCs) as drugs, particularly against low-druggability targets such as protein-protein interactions, has been widely discussed. There is little information, however, to guide ...
  • Function-driven, graphical design tool for microfluidic chips: 3DuF 

    Lippai, Joshua; Sanka, Radhakrishna; Lashkaripour, Ali; Densmore, Douglas (International Workshop on Bio-Design Automation (IWBDA), 2017-08)
    The use of microfluidic chips for applications in biology to reduce the cost, time, and difficulty of automating experiments, while promising, has proven to have barriers to entry. In particular, the cost of the equipment ...
  • mLSI design with MINT 

    Sanka, Radhakrishna; Densmore, Douglas; Lippai, Joshua (IWBDA, 2017-08)
    Fluigi is a microfluidic design framework that allows researchers to realize abstract descriptions of liquid flow relationships automatically as physical devices and corresponding control software. Its goal is to provide ...
  • MINT - Microfluidic Netlist 

    Sanka, Radhakrishna; Huang, Haiyao; Silva, Ryan; Densmore, Douglas (IWBDA, 2016-03)
    Fluigi is a microfluidic design framework that allows researchers to realize abstract descriptions of liquid flow relationships automatically as physical devices and corresponding control software. Its goal is to provide ...
  • Fluigi Cloud - A cloud CAD platform for microfluidics 

    Sanka, Radhakrishna; Subacius, Kestutis; Kapadia, Priya; Densmore, Douglas; McCormack, Shane; Asthana, Anish (IWBDA, 2017-08)
    With microfluidic large scale integration and the emergence of many new synthetic biology technologies, there is an ever increasing benefit in using computer automated design (CAD) tools for scaling designs to larger and ...
  • Design automation based on fluid dynamics 

    Lashkaripour, Ali; Sanka, Radhakrishna; Lippai, Joshua; Densmore, Douglas (International Workshop on Bio-Design Automation (IWBDA), 2017-08)
    Microfluidic devices provide researchers with numerous advantages such as high throughput, increased sensitivity and accuracy, lower cost, and reduced reaction time. However, design, fabrication, and running a microfluidic ...
  • Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens 

    Mahalanabis, Madhumita; Chang, Jessie; Carey, Brendan; Hsieh, Christopher; Stanley, Ahjegannie; Feldman, James; Mitchell, Patricia; Klapperich, Catherine; Odell, Christine A.; Pollock, Nira R.; Qingqing, Cao (2012-03-22)
    A rapid, low cost, accurate point-of-care (POC) device to detect influenza virus is needed for effective treatment and control of both seasonal and pandemic strains. We developed a single-use microfluidic chip that integrates ...
  • Awareness, interest, and preferences of primary care providers in using point-of-care cancer screening technology 

    Vanture, Sarah; Cho, Margaret; Wang, Catharine; Klapperich, Catherine; Huang, Franklin W.; Kim, Chloe S. (2016-01-15)
    Well-developed point-of-care (POC) cancer screening tools have the potential to provide better cancer care to patients in both developed and developing countries. However, new medical technology will not be adopted by ...
  • Many Microbe Microarrays Database: Uniformly Normalized Affymetrix Compendia with Structured Experimental Metadata 

    Faith, Jeremiah J.; Driscoll, Michael E.; Fusaro, Vincent A.; Cosgrove, Elissa J.; Hayete, Boris; Juhn, Frank S.; Schneider, Stephen J.; Gardner, Timothy S. (Oxford University Press, 2008-1)
    Many Microbe Microarrays Database (M3D) is designed to facilitate the analysis and visualization of expression data in compendia compiled from multiple laboratories. M3D contains over a thousand Affymetrix microarrays for ...

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