Effect of dosage form and total dietary fat on omega-3 fatty acid metabolism in man
Date
1991
DOI
Authors
Kowalchuk, Marilyn Burton
Version
OA Version
Citation
Abstract
Within the last two decades interest has been generated regarding the biochemistry, physiology and metabolism of omega-3 fatty acids. They appear to have a variety of biological actions that
influence platelet aggregability, inflammation, lipid levels and blood
pressure. The low incidence of cardiovascular disease and certain
inflammatory diseases found in the Greenland Eskimo population has
been attributed to a diet rich in omega-3 fatty acids, particularly
eicosapentaenoic acid and docosahexaenoic acid. It has been reported
that absorption of omega-3 fatty acids can be altered by both the
dosage form and the total amount of dietary fat consumed.
To assess ways of enhancing the pharmacological effects of
omega-3 fatty acid in man, we administered omega-3 fatty acids,
providing 4.8 grams per day as eicosapentaenoic acid (EPA) for four
weeks as either triglycerides (TG) or ethyl ester (EE) to four groups of ... [TRUNCATED]
Description
Thesis (D.Sc.D.)--Boston University. Henry M. Goldman School of Graduate Dentistry, 1991 (Nutritional Sciences)
Bibliography: leaves 141-159.
Bibliography: leaves 141-159.
License
This work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author.