Correlation between periodontal disease and coronary artery disease by endothelial function
Date
2000
DOI
Authors
Loukideli, Maria-Anna
Version
OA Version
Citation
Abstract
Epidemiological and intervention studies have suggested that infections are risk factors for coronary heart disease (CHD). Dental infections have appeared as cardiovascular risk factors in cross-sectional and in follow-up studies, and the association has been independent of the “classic” coronary risk factors. To examine the role of chronic bacterial infections as risk factors for coronary heart disease the association between periodontal disease and coronary artery disease was investigated. The purpose of this preliminary study was to correlate the severity of periodontal disease with coronary artery disease as evidenced by endothelium-derived nitric oxide (EDNO) determination. A total of 31 subjects were recruited in this study. Each subject was assigned to a group. Experimental group comprised 18 subjects affected by periodontal disease, and the control group comprised 13 age and sex-matched subjects with no signs of periodontal disease. All periodontal subjects had at least 3 teeth affected by periodontal disease as determined by clinical attachment, probing depth measurements, and radiographic evaluation. Control patients had no sign of periodontal disease. Experimental group subjects were further stratified according to their periodontal condition, and disease severity -moderate or advanced- as defined by the American Dental Association. The moderate periodontitis group comprised 5 subjects and the advanced periodontitis group 13 subjects.
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Description
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Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Dental Medicine, 2000 (Oral Biology).
Includes bibliographical references (leaves 52-68).
Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Dental Medicine, 2000 (Oral Biology).
Includes bibliographical references (leaves 52-68).
License
This work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.