Effect of dietary phosphate supplementation on the healing of experimental fibular fracture in the rats

Date
1970
DOI
Authors
Mesgarzadeh, Abolhassan
Version
OA Version
Citation
Abstract
A qualitative as well as a quantitative assessment of the effects of dietary phosphate on fibular fracture healing of rats was carried out. Dietary phosphate supplementation was found to accelerate the rate of the healing of fibular fracture by early formation and maturation of bony trabeculae in the line of fracture. High intake of phosphorus (1.8%) did not cause a change in the calcium and phosphorus content of the fractured or intact fibulae and adjoining tibias. Growth of the rats was inhibited when given a diet containing 3.6% phosphorus, whereas it remained unaffected with a diet containing l.8% phosphorus. The results of the present study suggest that phosphorus probably enhances the rate of fracture healing by stimulating the growth of the cells responsible for the repair processes and thus, predisposing a matrix for mineral deposition at the site of fracture.
Description
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Thesis (M.Sc.D.)--Boston University school of Graduate Dentistry. Dept. of Oral Surgery.
Bibliography included.
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