Evaluating ocular pain through MRI in patients with concussion
OA Version
Citation
Abstract
Ocular pain is a prevalent symptom that impacts many patients of mTBI. Chronic exposure to this pain and other chronic pain symptom associated with mTBI can lead to effects on the central nervous system, however how this pain occurs is not well understood. The aim of this study was to evaluate the differences in functional connectivity between subjects with mTBI and healthy subjects at resting state, and to evaluate the differences in pain reporting between subjects with mTBI and healthy subjects. The basal ganglia, prefrontal cortex, hippocampus and occipital lobe were found to have increased connectivity in subjects with mTBI over healthy subjects in resting state conditions. Additionally, subjects with mTBI reported higher pain symptoms through PHQ, PCSS and VLSQ8 questionnaires than healthy subjects. Cohort differences demonstrated how functional connectivity and pain symptoms are altered under conditions of chronic pain from mTBI.
Description
2025