Lipid risk profile in different ethnic groups after Roux-en-Y gastric bypass operations for morbid obesity
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Abstract
Background. Bariatric surgery is currently the most effective treatment for severe obesity. Roux-en-Y gastric bypass (RYGB) has emerged as the surgical procedure of choice due to its favorable risk-benefit profile. It has also been reported to remit type 2 diabetes and to reduce rates of cardiovascular disease by lipid profile improvement. However, there are no longitudinal data that address lipid profiles in different ethnic groups following bariatric surgery. The goal of this study was to determine whether race/ethnicity affects reduction in lipid levels after Roux-en-Y gastric bypass operations. Methods. Retrospective chart reviews were conducted for 913 consecutive obese patients undergoing gastric restrictive surgery in Boston Medical Center from 2004 to 2010. For these analyses, we included 825 patients consisting of 166 African Americans, 505 Caucasian Americans and 154 Hispanic Americans with 2 years of follow-up data. Mean levels for lipids and glycemic control were compared with ANOVA and longitudinal mixed linear modeling. [TRUNCATED]
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Thesis (M.A.)--Boston University
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