Kim, Kaa Yeong2022-06-062022-06-0619841984b14407863https://hdl.handle.net/2144/44606PLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please click Download and log in with a valid BU account to access. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.Thesis (M.Sc.D.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1984, (Pedodontics/Nutritional Science)Bibliography: leaves 52-64.The purpose of this study was to evaluate the two bio-flavonoids, hesperidin and neohesperidin dihydrochalcone, on dental caries and periodontal disease in the albino rat. Twenty-five-day-old male rats were fed the experimental diets for 42 days in this work. The bioflavonoid naringin was also fed for another comparison, since this bioflavonoid had been previously studied in this laboratory. At the end of the 42-day experimental period, the tooth surfaces were examined under a dissecting microscope. The sulcular caries lesions were recorded in all groups; the first molars were more affected than the second and third molars. The biggest difference was seen between the control and neohesperidin dihydrochalcone or hesperidin groups with the P values of 0.01 to 0.05. [TRUNCATED]en-USThis work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.Dental cariesBioflavonoidsCariostatic agentsThesis/Dissertation