Said, Yousri Z.2018-09-182018-09-1819751975https://hdl.handle.net/2144/31299Thesis (M.Sc.D.)--Boston University, School of Graduate Dentistry, 1975. Periodontology.Includes bibliographic references: leaves 112-131.One hundred-twenty subjects were assigned to AP-100 enzyme mouthwash, used twice daily, in a doubleblind treatment schedule for six weeks. They were divided equally into Part A and Part B, sixty subjects each. In Part A, subjects ,vere scored, then half of them were randomly assigned to placebo and half to AP-100 enzyme. Removal of pre-existing plaque and treatment of gingivitis only were considered in this part. Part B, focused on reducing plaque accumulation and treatment of gingivitis. Therefore, all subjects in Part B underwent complete prophylaxis with a base line score equal to zero. Gingivitis only was scored in this group and the subjects were randomly assigned half to AP-100 and the other half to placebo. Plaque and gingivitis were scored at three and six weeks. [TRUNCATED]en-USThis work is being made available in OpenBU by permission of its author, and is available for research purposes only. All rights are reserved to the author.Dental plaquePrevention & controlPeriodontologyThesis/Dissertation