Myers, R. H.Sax, D. S.Schoenfeld, M.Bird, E. D.Wolf, P. A.Vonsattel, J. P.White, R.F.Martin, J. B.2009-10-172009-10-171985Myers, R. H., Sax, D. S., Schoenfeld, M., Bird, E. D., Wolf, P. A., Vonsattel, J. P., White, R. F., & Martin, J. B. (1985). Late onset of huntington's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 48(6), 530-534.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1028368/?tool=pmcentrezhttps://hdl.handle.net/2144/1208Twenty-five patients with late-onset Huntington's disease were studied; motor impairment appeared at age 50 years or later. The average age at onset of chorea was 57.5 years, with an average age at diagnosis of 63.1 years. Approximately 25% of persons affected by Huntington's disease exhibit late onset. A preponderance of maternal transmission was noted in late-onset Huntington's disease. The clinical features resembled those of mid-life onset Huntington's disease but progressed more slowly. Neuropathological evaluation of two cases reveal less severe neuronal atrophy than for mid-life onset disease.Article