Daraj, Hana Hasan2018-10-312018-10-3120122012(OCoLC)903903530(OCoLC)ocn903903530https://hdl.handle.net/2144/31790PLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please click Download and log in with a valid BU account to access. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.Thesis (MSD) --Boston University Institute for Dental Research and Education, Dubai, 2012 (Prosthodontics).Includes bibliographic references: leaves 45-54.PURPOSE: The purpose of this in vitro study is to assess the effect of ozone cream on C. albicans on acrylic resin denture plates. METHODS: 120 experimental denture plates were prepared with heat-polymerized acrylic resin (15mm XI5 mm X 3 mm; Dentsply, LUCITONE 199 Resin, York, PA) according tothe manufacturer's instructions, were contaminated with C. albicans then treated with ozonated cream. Results were compared with contaminated plates in ultrasonic sterile water as a negative control group and contaminated plates treated with chlorhexidine as a positive control group. • Thirty acrylic resin surfaces were polished with pumice and rubber wheels and treated with ozonated cream Pol-Oz • Thirty acrylic resin surfaces were polished with pumice and rubber wheels and treated with ultrasonic sterile water. Pol-Wat (Negative Control) • Thirty acrylic resin surfaces were polished with pumice and rubber wheels and treated with chlorhexidine. Pol-CHX (Positive Control) • Thirty acrylic resin surfaces were rough and were treated with ozonated cream. Rou-Oz After treatment, the number of attached C. albicans was counted by using optical microscope. RESULTS: The analysis demonstrated that here were statistically significant differences amongst the four groups. A p=0.017 was observed when Pol-Wat was compared with Rou-oz group. In addition, there was a significant reduction in the colony count when comparing the Pol-Wat with Pol-Oz group (p=0.001). Furthermore, the p values for Pol-Oz were significantly lower when compared with the remaining three groups (p= 0.00001, 0.00001 and 0.001 respectively). CONCLUSION: Ozone cream was highly effective for inhibiting C. albicans in pure cultures on polished denture acrylic resin plates.en-USThis work is protected by copyright. Downloading is restricted to the BU community. If you are the author of this work and would like to make it publicly available, please contact open-help@bu.edu.Candida albicansAnti-infective agentsThesis/Dissertation99208053381001161