Li, JunjieZhang, WeixiaChung, Ting-FungSlipchenko, Mikhail N.Chen, Yong P.Cheng, Ji-XinYang, Chen2018-02-132018-02-132015-07-23Junjie Li, Weixia Zhang, Ting-Fung Chung, Mikhail N Slipchenko, Yong P Chen, Ji-Xin Cheng, Chen Yang. 2015. "Highly sensitive transient absorption imaging of graphene and graphene oxide in living cells and circulating blood.." Sci Rep, Volume 5:12394.2045-2322https://hdl.handle.net/2144/27001We report a transient absorption (TA) imaging method for fast visualization and quantitative layer analysis of graphene and GO. Forward and backward imaging of graphene on various substrates under ambient condition was imaged with a speed of 2 μs per pixel. The TA intensity linearly increased with the layer number of graphene. Real-time TA imaging of GO in vitro with capability of quantitative analysis of intracellular concentration and ex vivo in circulating blood were demonstrated. These results suggest that TA microscopy is a valid tool for the study of graphene based materials.12394This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.http://creativecommons.org/licenses/by/4.0/Science & technologyNear-infrared absorbencyGrapheneCarbon nanotubesPhotothermal therapyStem cellsAnimalsComputer systemsGraphiteImage enhancementMicroscopyMolecular imagingOxidesRatsRats, Long-EvansReproducibility of resultsSensitivity and specificityArticle10.1038/srep123940000-0002-5607-6683 (Cheng, Ji-Xin)0000-0001-9454-847X (Yang, Chen)